Pharm 3 Ca Flashcards
1
Q
Glucocorticoids effect
A
- Decrease Vit D, Ca in intestine
- Increase Ca clearance, bone resorption
2
Q
PTH drug
A
Teriparatide acetate
- Tx osteoporosis
- do not infuse (resorption)
3
Q
Teriparatide acetate SE
A
- Osteosarcoma in rats
- Don’t use in paget’s disease
4
Q
Active vitamin D
A
Calcitriol (1,25)
5
Q
Calcitonin indication
A
Paget (relieve pain)
-osteoporosis
6
Q
Bisphosphonate MOA
A
Bind to hydroxyapatite, poisons osteoclasts
7
Q
Bisphosphonate SE
A
- Upper GI irritation
- Osteonecrosis of jaw
- Atypical femoral fractures
8
Q
Denosumab SE
A
same as bisphosphonates
9
Q
Denosumab CI
A
hypocalcemia
10
Q
Denosuma MOA
A
anti-RANKL Ab
11
Q
Estrogen therapy MOA
A
Increase OPG production
