Path 3 Testes Flashcards by Philip Lichtenstein | Brainscape

Q

Interstitial testicular cells

A

Leydig cells

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Q

Testicular hematoma

A

Pseudotumor cystic cavity filled with blood

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Q

Testicular hydrocele cause

A

Incomplete closure of processus vaginalis

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Q

Spermatocele cause

A

Abnormal connection between epididymis and tunica vaginalis

-Clinically felt as third testis

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Q

Testicular atrophy genetic cause

A

Klinefelter’s syndrome (XXY)

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Q

Chronic orchitis cause

A

Mumps

1 week after swelling of parotid glands

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Q

Granulomatous orchitis

A

May be idiopathic (50 y/o)

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Q

Tuberculous orchitis

A

Begins in epididymis, spreads to testis

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Q

Testicular tumors

A

Always malignant, derived from germ cells

-Sertoli or Leydig cell tumors are benign

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Q

Testicular tumor genetics

A

Isochromosome on the short arm of ch 12

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Q

Seminoma

A

May show hCG Syncytiotrophoblasts

PLAP positive
Dense lymphocytic infiltrate

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Q

Spermatocytic Seminoma

A

Benign

-No lymphocytes, syncytiotrophoblasts

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Q

Embryonal carcinoma

A

Often metastasizes to retroperitoneal lymph nodes

-Tx aggressively

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Q

Endodermal sinus tumor

A

Yolk sac tumor (variant of embryonal)

Schiller-Duval bodies (perivascular)
AFP positive

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Q

Testicular teratomas

A

Potentially malignant

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Q

Testicular choriocarcinoma

A

Syncitiotrophoblasts (placenta)

Hemorrhagic
Metastasize aggressively to lung

Q

Leydig cell adenoma

A

Precocious puberty, gynecomastia

-Reinke crystals

Q

Seminoma

A

May show hCG Syncytiotrophoblasts

PLAP positive
Dense lymphocytic infiltrate

Q

Spermatocytic Seminoma

A

Benign

-No lymphocytes, syncytiotrophoblasts

Q

Embryonal carcinoma

A

Often metastasizes to retroperitoneal lymph nodes

-Tx aggressively

Q

Endodermal sinus tumor

A

Yolk sac tumor (variant of embryonal)

Schiller-Duval bodies (perivascular)
AFP positive

Q

Testicular teratomas

A

Potentially malignant

Q

Testicular choriocarcinoma

A

Syncitiotrophoblasts (placenta)

Hemorrhagic
Metastasize aggressively to lung

Q

Leydig cell adenoma

A

Precocious puberty, gynecomastia

-Reinke crystals