Micro 5 Syphilis Flashcards
1
Q
Syphilis micro
A
Axial filament between peptidoglycan and outer layer
2
Q
Secondary syphilis
A
3-6 months
- Rash on palms and soles
- Condylomata lata
- Systemic symptoms
3
Q
Syphilis rash similar to
A
Rocky Mountain Spotted Fever
4
Q
Tertiary syphilis
A
Neuro/cardiovascular syphilis
-Gummas in bone, skin, liver, brain
5
Q
Congenital syphilis
A
- Hepatosplenomegaly
- Rhinitis (snuffles)
- Skin rash (2ndary syph)
6
Q
T. pallidum endemicum
A
Endemic syphilis (Bejel)
- Tropical disease of children
- Granulomas /gummas of skin, bones, nasopharynx
7
Q
T. pallidum pertenue
A
Yaws
- Tropical disease of children
- Granulomas/gummas of skin, bones
8
Q
T. pallidum carateum
A
Pinta
- Tropical disease of children
- Small, hypopigmented, pruritic papules
9
Q
T. pallidum visual identification
A
Darkfield microscopy
- Direct fluorescent Ab detection
- Doesn’t work for tertiary syphilis
10
Q
T. pallidum blood tests
A
-RPR, VDRL (anti-cardiolipin Ab)
11
Q
Syphilis Tx problem
A
Jarisch-Herxheimer rxn
- Acute systemic rxn due to sudden release of treponemal antigens
- Tx with steroids
