Path 10 Placenta Flashcards
Bleeding + cervix open/closed abortion
Open = Inevitable abortion Closed = Threatened abortion
Maternal causes of spontaneous abortion
Diabetes, fibroids, uterine malformation
Systemic causes of spontaneous abortion
Antiphospholipid antibody syndrome
- Coagulopathies
- HTN
Infections causing spontaneous abortion
Toxoplasma
Mycoplasma
Listeria
Adnexal mass
Ectopic pregnancy
Placenta previa
Placenta implanted in lower uterus or cervix
-Happens with previous C-section
Placenta accreta
Placental villi bypass decidua, implante chorionic villi into myometrium
Chorioamnionitis risk
- Premature rupture of membranes
- Group B strep
Placental abruption
Placenta separates from decidua prior to delivery
- Causes stillbirth, maternal DIC
- Risk from cocaine, HTN, multiparity
Pre-eclampsia
HTN, proteinuria, edema
-May have headaches, visual disturbance
Eclampsia
Pre-eclampsia with seizures
HELLP
Pre-eclampsia with thrombotic microangiopathy
-Hemolysis, Elevated Liver enzymes, Low Platelets
Pregnancy toxemia general
20 weeks -> birth
- Primigravidas
- Placental infarcts/hemorrhage
Partial mole
Normal ovoid, 2 sperms (triploid, 69 XXY)
- Fetal tissue present
- Minimal risk of choriocarcinoma
- Some hydropic villi w/focal trophoblastic proliferation
Complete mole
Empty ovum, 2 sperms (diploid, 46 XX)
- Absent fetal tissue
- All hydropic villi with diffuse trophoblastic proliferation
- Higher risk of choriocarcinoma
