Peripheral Nervous System Path Quiz 5

Question 1

Wallerian degeneration is a process that results when

Answer 1

a nerve fiber is cut or crushed, in which the part of the axon separated from the neuron’s cell body degenerates distal to the injury.
occurs within 24-36 hrs

Question 2

Bell’s palsy involves which cranial nerve?

Answer 2

facial nerve

Question 3

how to differentiate a stroke from Bell’s palsy?

Answer 3

stroke- can wrinkle forehead

BP- can’t wrinkle forehead

Question 4

associated etiology for bell’s palsy?

Answer 4

HSV1

Question 5

many cases of trigeminal neuralgia are caused by

Answer 5

blood vessel compression of the trigeminal nerve root at the pons

Question 6

oculomotor nerve palsy is also known by which sx?

Answer 6

“down and out” symptoms,

lateral downward deviation

Question 7

in carpal tunnel syndrome you have sx along which nerve?

Answer 7

median nerve

Question 8

what’s the hallmark sign of carpal tunnel syndrome?

Answer 8

thenar eminence atrophy

Question 9

what’s the characteristic sign of ulnar nevre injury or ulnar nerve palsy?

Answer 9

claw hand deformity

sx affecting 4th and 5th digits

Question 10

Meralgia paresthetica affects which nerve?

Answer 10

lateral cutaneous nerve of the thigh

Question 11

Meralgia paresthetica is more common in obese patients. why?

Answer 11

increased mechanical stress on the inguinal ligament

Question 12

presumed pathogenesis of diabetic neuropathy?

Answer 12

sorbitol and inositol
ischemia
microvascular disease

Question 13

the most common cause of immune or inflammatory polyneuropathies is

Answer 13

Guillain-Barré syndrome (GBS)

Question 14

Guillain-Barré syndrome (GBS) is characterized by

Answer 14

ascending paralysis

Question 15

Botulism is characterized by

Answer 15

descending paralysis

Question 16

which vitamin deficiency is tied to neuropathy?

Answer 16

Vit B1 (thiamin)

Question 17

a vitamin B1 deficiency that causes neuropathy is called?

Answer 17

Beriberi

Question 18

pathogenesis of botulism

Answer 18

botulinum toxin blocks presynaptic nerve preventing release of Ach
its NOT Ab mediated

Question 19

what bugger cause leprosy?

Answer 19

Mycobacterium leprae

Question 20

Mycobacterium leprae under microscope

Answer 20

bacilli-shaped bacterium that doesn’t take up stain very well, unless treated with acid (acid fast)

Question 21

how does lyme differ from bell’s palsy?

Answer 21

Lyme is a bilateral facial neuropathy

Question 22

microscopic appearance of herpes zoster lesion

Answer 22

multinucleated giant cell

Question 23

shingles at the tip of the nose

Answer 23

Hutchinson’s sign

Question 24

acoustic neuroma (a vestibular schwannoma) involves which nerve?

Answer 24

verstibulocochlear nerve (CN VIII)

Question 25

microscopically neurofibroma appears

Answer 25

spindle shaped
darkly staining
large cells

Question 26

Neurofibromatosis type 1 is characterized by

Answer 26

multiple small cutaneous neurofibromas

cafe au lait spots

Question 27

Neurofibromatosis type 2 is the result of a mutation of which protein?

Answer 27

protein merlin

Question 28

hallmark of neurofibromatosis type 2 is

Answer 28

hearing loss due to acoustic neuromas around the age of twenty

Question 29

perineuromas are characterized by

Answer 29

elongated cells in parallel bundles