Endocrine Path Quiz 3- part 1

Question 1

the most common cause of hyperpituitarism is

Answer 1

an adenoma arising in the anterior lobe (pituitary adenoma)

Question 2

________ accounts for about 15% of all intracranial neoplasms

Answer 2

pituitary adenoma

Question 3

majority of pituitary adenomas are incidentally diagnosed microadenomas, aka _______

Answer 3

incidentaloma

Question 4

microscopic view of a pituitary adenoma reveals

Answer 4

small round cells that are identical in appearance
cells may be arranged in nests or cords
prominent vascularity

Question 5

most frequent type of functioning pituitary adenoma is

Answer 5

prolactinoma

Question 6

acute hemorrhage of an adenoma is termed

Answer 6

pituitary apoplexy

Question 7

necrosis of the pituitary gland due to hemorrhage and hypovolemic shock during peri-partum period is termed

Answer 7

Sheehan’s syndrome

Question 8

is the posterior pituitary affected in Sheehan’s syndrome?

Answer 8

not usually due to it’s direct blood supply

Question 9

most common (but rare) hypothalamic suprasellar tumor is

Answer 9

craniopharyngioma

Question 10

Craniopharyngioma has a ______ distribution

Answer 10

bimodal age

one peak in childhood, second peak in adults > 65

Question 11

microscopically craniopharyngioma reveals

Answer 11

palisading cells “waterfall configuration” 
lamellar quality (stacked), wet keratinization - smooth and non-cellular area

Question 12

METS to the brain is more common than primary brain cancer. What are the two most common sources of cancer that METS to the pituitary?

Answer 12

*breast and lung

also prostate and melanoma