Joint Path Quiz 4

Question 1

most common cause of secondary osteoarthritis?

Answer 1

DM

also hemochromatosis and Wilson’s disease

Question 2

x-ray of OA shows

Answer 2

jnt space narrowing
osteophyte formation (bony outgrowths)
subchondral bone cysts
sclerosis

Question 3

Hands of person with OA classically shows

Answer 3

Herbeden nodes distally (DIPs)

Bouchard’s nodes proximally (PIPs)

Question 4

RA is characterized as

Answer 4

an auto-immune disease

Question 5

RA is commonly (~ 80% of cases) associated with a group of anti-IgG autoantibodies called

Answer 5

rheumatoid factors (RF)

Question 6

in RA, what changes are taking place at the level of the joint?

Answer 6

the synovial membrane becomes grossly enlarged, congested, edematous, and thickened

Question 7

microscopically RA appears with

Answer 7

multiple layers of proliferation of synoviocytes

Question 8

which lab IS highly specific for RA?

Answer 8

anti-CCP (aka ACPAs)

Question 9

what x-ray finding is characteristic for ankylosing spondylitis?

Answer 9

“bamboo spine”

due to vertebral body fusion

Question 10

Reactive arthritis is known for which constellation of sx?

Answer 10

arthritis, non-gonococcal urethritis or cervicitis, and conjunctivitis

Question 11

reactive arthritis is due to either GI infection or GU infection. Which bug is the most commonly associated GU infection?

Answer 11

Chlamydia

Question 12

which rash is associated with reactive arthritis?

Answer 12

keratoderma blennorrhagicum

Question 13

what is are two distinctive features of psoriatic arthritis?

Answer 13

nail pitting

onycholysis

Question 14

the number one cause of septic arthritis (aka supperative arthritis) in adults?

Answer 14

staphylococcus

Question 15

the number one cause of septic arthritis (aka supperative arthritis) in children?

Answer 15

H. influenza

Question 16

the number one cause of septic arthritis (aka supperative arthritis) in elderly?

Answer 16

E. coli

Question 17

distinguish septic arthritis from reactive arthritis

Answer 17

reactive arthritis refers to arthritis cause by an immune consequence of an infection, but not directly attributable to the infection itself
septic arthritis is the direct invasion of a joint by an infectious agent

Question 18

the number one cause of septic arthritis in young adults?

Answer 18

neisseria gonorrhoea

Question 19

Pott’s disease is characterized by

Answer 19

TB of the spine

Question 20

what’s the characteristic rash of Lyme disease?

Answer 20

Erythema migrans

Question 21

gout caused by

Answer 21

uric acid crystals (aka monosodium urate)

Question 22

pseudogout caused by

Answer 22

calcium pyrophosphate crystals

Question 23

most common benign tumor of the joints?

Answer 23

ganglion