pead dermatology Flashcards
eczema
dermatitis
itchy dry inflammatory skin disease
varicose eczema
oedema/venous insufficiency
atopic eczema/dermatitis
most common eczema esp in kids
inherited abnormality in skin - filaggrin expresion
filaggrin
binds keratin filaments together
role in producing natural moisturising factor
atopy
overreactive immune system response to environmental stimuli
3 commonly linked conditions: asthma, eczema, hayfever
atopic eczema distribution
infancy: starts face/neck then spreads more generally
older children: flextural pattern - antecubtial fossa, popliteal fossa, hands, wrists, ankles
atopic eczema: loss of skin barrier function
loss water
irritants may penetrate: soap, detergents, dirt
allergens may penetrate: pollens, dustmite, microbes
associations with childhood eczema flares
infection environment: central heating, cold air stress teething pets
seborrhoeic eczema
mainly scalp and face
scale assoc
often babies <3mo, resolves by 12mo
seborrhoeic eczema associations
proliferations of various species of skin commensal Malassezia in yeast form
cradle cap in infants
seborrhoeic eczema Mx
emolionts
anti-fungal creams
mild topical steroids
discoid eczema
scattered annular/circular patches of itchy eczema
can occur in this pattern with atopic dermatitis or in isolatoin
prophylx eczema
hand and feet eczema
characterised by vesicles
intensely itchy
exogenous eczema
allergic eczema: sensitised to allergen, TIV hypersensitivity
irritant eczema: water + soap, irritant foods, citrus, tomatoes, chemical irritant
food allergy tI hypersensitivity
lip swelling
facial redness/itching
food allergy TIV
worsening eczema 24/48hrs after GI probs FTT severe eczema unresponsive to Rx severe generalised itch
food allergy and eczema: Ix
TI: IgE, skin prick testing
TIV: restriction/elimination diet
eczema Rx options
emolients topical steroids calcineurin inhibitors: protopic UBV light therapy immunosuppresion
topical steroids: potency
very potent - demotove 600x
potent - betnovate 100x
moderate - eumovate 25x
mild - hydrocortisone