osteosarcoma Flashcards

1
Q

age usually presents

A

adolescents and younger adults aged 10-20

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2
Q

most common sites

A

femur is most common

tibia
humerus

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3
Q

presentation

A

persistent bone pain, worse at night
can disturb sleep

bone swelling
palpable mass
restricted joint movements

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4
Q

Mx - children presenting with unexplained bone pain or swelling

A

very urgent direct access x-ray within 48hrs

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5
Q

Mx - xray suggests possible sarcoma

A

very urgent specialist assessment within 48hrs

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6
Q

xray findings

A

poorly defined lesion

  • destruction of normal bone
  • fluffy appearance

periosteal reaction with sun-burst appearance

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7
Q

blood test results

A

raised ALP

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8
Q

Mx

A

surgical resection , often with limb amputation

adjuvant chemotherapy

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9
Q

main complications

A

pathological bone fractures

metastasis

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