JIA Flashcards
diagnosed where there is
arthritis w/o any other cause lasting >6wks in patient <16yrs
key features inflammatory arthritis
joint pain
swelling
stiffness
systemic JIA: aka
still’s disease
systemic JIA: features
salmon-pink rash high swinging fevers enlarged lymph nodes weight loss joint inflammation and pain splenomegaly muscle pain pleuritis pericarditis
systemic JIA: blood results
ANA and RF usually -ve
raised inflammatory markers: CRP, ESR, platelets
systemic JIA: key complication
macrophage activation syndrome
macrophage activation syndrome: what
severe activation of immune system with massive inflammatory response
macrophage activation syndrome: presentation
acutely unwell child DIC anaemia thrombocytopenia bleeding
macrophage activation syndrome: key investigation finding
low ESR
non-infective differentials for kid with fever > 5 days
kawasaki disease
systemic JIA
rheumatic fever
leukaemia
polyarticular JIA: what
idiopathic inflammatory arthritis in ≥5 joints
polyarticular JIA: systemic symptoms
mild
mild fever, anaemia, reduced growth
polyarticular JIA: seronegative
negative RF
polyarticular JIA: seropositive
positive RF
usually older children and adolescents
disease pattern more similar to RA in adults
oligoarticular JIA: aka
pauciarticular JIA