JIA Flashcards

1
Q

diagnosed where there is

A

arthritis w/o any other cause lasting >6wks in patient <16yrs

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2
Q

key features inflammatory arthritis

A

joint pain
swelling
stiffness

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3
Q

systemic JIA: aka

A

still’s disease

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4
Q

systemic JIA: features

A
salmon-pink rash 
high swinging fevers
enlarged lymph nodes
weight loss
joint inflammation and pain 
splenomegaly 
muscle pain 
pleuritis
pericarditis
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5
Q

systemic JIA: blood results

A

ANA and RF usually -ve

raised inflammatory markers: CRP, ESR, platelets

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6
Q

systemic JIA: key complication

A

macrophage activation syndrome

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7
Q

macrophage activation syndrome: what

A

severe activation of immune system with massive inflammatory response

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8
Q

macrophage activation syndrome: presentation

A
acutely unwell child 
DIC
anaemia 
thrombocytopenia 
bleeding
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9
Q

macrophage activation syndrome: key investigation finding

A

low ESR

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10
Q

non-infective differentials for kid with fever > 5 days

A

kawasaki disease
systemic JIA
rheumatic fever
leukaemia

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11
Q

polyarticular JIA: what

A

idiopathic inflammatory arthritis in ≥5 joints

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12
Q

polyarticular JIA: systemic symptoms

A

mild

mild fever, anaemia, reduced growth

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13
Q

polyarticular JIA: seronegative

A

negative RF

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14
Q

polyarticular JIA: seropositive

A

positive RF

usually older children and adolescents
disease pattern more similar to RA in adults

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15
Q

oligoarticular JIA: aka

A

pauciarticular JIA

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16
Q

oligoarticular JIA: what

A

involves 4 joints or less

usually only one joint

17
Q

oligoarticular JIA: tends to affect

A

larger joints

girls < 6yrs

18
Q

oligoarticular JIA: classic assoc feature

A

anterior uveitis

19
Q

oligoarticular JIA: antibodies

A

ANA usually +

RF usually -

20
Q

enthesitis related arthritis: what

A

paediatric version of seronegative spondyloarthropathy group affecting adults

21
Q

juvenile psoriatic arthritis: what

A

seronegative inflammatory arthritis assoc with psoriasis

22
Q

juvenile psoriatic arthritis: pattern

A

can be symmetrical affecting small joints
or
assymetrical affecting large joints

23
Q

juvenile psoriatic arthritis: signs OE

A
psoriatic plaques
nail pitting 
onycholysis 
dactylitis
enthesitis
24
Q

Mx JIA

A

NSAIDs
steroids: oral, IM, IA
DMARDs
biologics - etanercept, infliximab