paediatric respiratory - asthma Flashcards
solution to asthma
- no wheeze no asthma
- tests may help decision
- if QoL affected confirm diagnosis with trial of ICS, QoL not affected watch and see
no wheeze
no asthma
what is asthma key features
wheeze
variability
respond to treatment
inconsistencies of asthma
- ‘transient’ vs persistent
- different severities
- different age at onset
- heterogeneity in response
- different triggers
asthma syndromes
infant onset childhood onset adult onset excertional asthma occupational asthma
what causes asthma? what we know
1/host response to environment
2/infection important
3/physiology abnormal before symptoms
4/it is a syndrome
what causes asthma
genes
interact with environment
epigenetics
primary epithelial abnormality (skin/airway/gut) results in eczema, asthma etc or allergy (which fuels asthma)
genes load gun and environment pulls tigger
deciding when is it asthma
all in history
examination unhelpful
no diagnostic test in kids
tests can be useful for excluding things
asthma diagnosing in children: NICE
- spirometry
- broncho-dilatory response
- exhaled nitric oxide
- peak flow
what is asthma characterised by
wheeze
cough
episodes SOB
SOB at rest
<30% lung function - signif resp difficulty
asthma cough
dry
at night
exertional
asthma treatment
ICS for 2 months
ideal diagnostic criteria for asthma
wheeze (with and without URTI)
SOB at rest
parental asthma
responds to treatment
differential diagnoses for ‘asthma’
under 5
- congenital
- CF
- PCD
- bronchitis
- foreign body
5+
- dysfunctional breathing
- vocal cord dysfunction
- habitual cough
- pertussis