Pathology - Neoplastic and None neoplastic growth disorders Flashcards

1
Q

what is an increase in the size of a cell/tissue without cell division known as?

a. hypertrophy
b. hyperplasia
c. atrophy
d. metaplasia

A

a.hypertrophy

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2
Q

what does hypertrophy often occur in conjunction with?

a. hypertrophy
b. hyperplasia
c. atrophy
d. metaplasia

A

b.hyperplasia

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3
Q

in systemic hypertension, increased afterload and aortic stenosis what happens to the cardiac muscle of the left ventricle

a. hypertrophy
b. hyperplasia
c. atrophy
d. metaplasia

A

a.hypertrophy

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4
Q

what is an increase in the number of cells in a tissue as a consequence of cell division known as?

a. hypertrophy
b. hyperplasia
c. atrophy
d. metaplasia

A

b.hyperplasia

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5
Q

adaptive increase in erythrocyte production in high altitude is an example of which change?

a. hypertrophy
b. hyperplasia
c. atrophy
d. metaplasia

A

b.hyperplasia

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6
Q

where is eryhtropoeitin released from?

a. liver
b. bone marrow
c. kidney

A

c.kidney

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7
Q

psoriasis (too many keratinocytes) and enlarged prostate are caused by which change ?

a. hypertrophy
b. hyperplasia
c. atrophy
d. metaplasia

A

b.hyperplasia

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8
Q

enlarged prostate putting pressure on which organ in benign prostatic hyperplasia causes difficulty urinating, frequent need to urinate and difficulty emptying the bladder?

a. ureter
b. bladder and urethra
c. urethra

A

b.bladder and urethra

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9
Q

a decrease in the size of an organ that can be due to a decrease in cell size or number is known as?

a. hypertrophy
b. hyperplasia
c. atrophy
d. metaplasia

A

c.atrophy

increased apoptosis/reduced proliferation

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10
Q

what happens to the brain in alzheimers disease?

a. hypertrophy
b. hyperplasia
c. atrophy
d. metaplasia

A

c.atrophy

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11
Q
A 75 year old male presents with urinary retention. PR examination 
shows symmetrical enlargement of the 
prostate. He is electively admitted for a 
TURP. The resected prostatic tissue is 
most likely to show
A. Atrophy of the prostatic glandular 
tissues
B. Benign nodular hyperplasia
C. Hypertrophy of bladder neck 
smooth muscle
D. Prostatic adenocarcinoma
E. Squamous Metaplasia
A

B. Benign nodular hyperplasia

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12
Q

the replacement with one type of mature differentiated cell type with another as an adaptive response to insult or injury is known as?

a. hypertrophy
b. hyperplasia
c. atrophy
d. metaplasia

A

d.metaplasia

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13
Q

cigarette smoke converts the normal pscc epithelium of the bronchi to what other type (metaplasia)

a. squamous
b. columnar

A

a. squamous

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14
Q

bladder stones converts the normal transitional epithelium of the urinary bladder to what other type (metaplasia)

a. squamous
b. columnar

A

a. squamous

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15
Q

gastrooesophageal reflux converts the normal squamous epithelium of the oesophagus to what other type (metaplasia)

a. transitional
b. columnar

A

b.columnar

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16
Q

in barrets oesophagus theres metaplasia from native squamous to what

a. glandular mucosa
b. transitional
c. cuboidal

A

a.glandular mucosa

17
Q

a reversible condition in which epithelial cells require some features of malignant cells but without the capacity for invasion is known as..

a. hypertrophy
b. hyperplasia
c. atrophy
d. metaplasia
e. dysplasia

A

e.dysplasia

18
Q

A 52 year old obese Caucasian male presents with severe heartburn and waterbrash.
At endoscopy, the oesophageal lining is abnormal in the distal 1/3 and shows a large irregular red flat area.There are no nodules or ulcers
Biopsies of the abnormal area are likely to show:
A. Adenocarcinoma
B. Barrett’s oeophagus
C. Dysplastic squamous epithelium
D. Herpes Simplex
E. Squamous cell carcinoma

A

B. Barrett’s oeophagus

19
Q

an abnormal mass of tissue due to genetic alterations the growth of which is uncoordinated with that of normal tissues and persists after removal of the evoking stimulus is known as..

a. tumour
b. neoplasm

A

b.neoplasm

20
Q

what type of tumour is usually well circumsised/encapsulated with few mitoses?

a. benign
b. malignant

A

a. benign

21
Q

what type of tumour is usually poorly defined or irregular with many mitoses?

a. benign
b. malignant

A

b. malignant

22
Q

in which type of tumour is nuclear morphology variable, along with resemblance to tissue of origin and common necrosis

a. benign
b. malignant

A

b. malignant

23
Q

adeno-

A

glandular epithelium

24
Q

papillo-

A

non glandular epithelium

25
Q

lipo-

A

fat

26
Q

osteo-

A

bone

27
Q

chondro-

A

cartilage

28
Q

angio-

A

blood vessel

29
Q

rhabdo-

A

skeletal muscle

30
Q

leiomyo-

A

smooth muscle

31
Q

what cancer has keratin pearls

a. adenocarcinoma
b. squamous cell carcinoma
c. squamous cell metaplasia

A

b.squamous cell carcinoma

32
Q

a low grade, well differentiated tumour has a..

a. less aggresive course
b. more aggressive course

A

a.less aggresive course

33
Q

a high grade, poorly differentiated tumour has a..

a. less aggresive course
b. more aggressive course

A

b.more aggressive course

34
Q

stage of a tumour refers to..

a. resemblance to presumed normal counterpart
b. size of a tumour
c. extent of spread of a tumour

A

c. extent of spread of a tumour

35
Q

what is the most common pathway of spread for carcinomas and melanomas

a.transcoelemic
b.lymphatic spread
c,haemotogenous spread

A

b.lymphatic spread

36
Q

what type of cancer does not usually spread by lymph

a. carcinoma
b. melanoma
c. sarcomas

A

c.sarcomas

37
Q

what spread is typical of sarcomas

a.transcoelemic
b.lymphatic spread
c,haemotogenous spread

A

c,haemotogenous spread

38
Q

which of these organs are not involved frequently in haemotogenous spread

a,liver

b. lungs
c. spleen

A

c. spleen

39
Q
Which of the following tumours is most likely to show lymphatic 
invasion?
A. Breast Carcinoma
B. Breast Fibroadenoma
C. Follicular Lymphoma
D. Well differentiated liposarcoma
E. Uterine Leiomyoma
A

A. Breast Carcinoma