Path final RA Flashcards

1
Q

granulation tissue associated with RA

A

Pannus

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2
Q

RA has both ______ and _____ degeneration

A

chemical, mechanical

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3
Q

Female to male ratio

A

4:1

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4
Q

RA etiology

A

unknown

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5
Q

nonsuppurative proliferative synovitis which in time leads to destruction of the articular cartilage and progressive disabling arthritis

A

RA

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6
Q

RAStarts as _____ arthritis in small joints in hands and feet.

A

symmetrical

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7
Q

RA usually starts on 1rst___ and___ (first symptoms) usually no____

A

pip, mcp

DIP

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8
Q

What kind of fluid is found inside the joints with RA

A

inflammatory exudate

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9
Q

inflammatory pattern

A

bad in morning, better as day goes on

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10
Q

Stiffness due to

A

accumulation of fluid

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11
Q

may decrease pain and chances of the joints being fused

A

physical activity

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12
Q

Rheumatoid hand

A

ulnar deviation of finders at MCP joints
Atrophy of intercostal and interossei muscles
inflammation of the wrist

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13
Q

TENOSYNOVITIS aka

A

ganglion

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14
Q

inflammation of tendon sheath-2 layers of fibrous tissue that surround tendons

A

TENOSYNOVITIS aka ganglion

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15
Q

caused by excess fluid production and cured by hydrocortisol

A

TENOSYNOVITIS aka ganglion

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16
Q

why should you never remove the ganglion that results from Tenosynovitis?

A

results in stenosing tendinitis

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17
Q

long term soft tissue inflammation will cause what?

A

bones in vicinity to lose density (osteopenia)

18
Q

osteopenia:due to _____ that cause activation of_____

A

cytokines, osteoclasts

19
Q

Causes decrease in articular contact

A

periarticular osteopenia (typical for any chronic inflammatory joint disease)

20
Q

med term without nerve interference.

A

subluxation

21
Q

no articulating bones with no joint function

A

Luxation

22
Q

swan neck deformity

A

hyperextension of PIP and flexion of DIP

23
Q

calosities in the ____ can cause a deformity called _____

A

MTPs, Hammertoes

24
Q

only part of joint with blood supply

A

synovial membrane(also has lots of nociceptors)

25
Q

Cartilage allows for _____ of joints

A

congruency

26
Q

2 functions of synovial fluid

A

lubricates joint surfaces

nourishes cartilage

27
Q

types of joint pathologies

A

inflammatory
degeneration
metabolic

28
Q

Genes associates with RA

A

HLA DR4, DR1

human leukocyte antigen

29
Q

how does panes (granulation tissue) affect the joint?

A

requires more and more room, but space is limited

30
Q

periarticular osteopenia can lead to

A

subluxation:slipping of bone resulting to loss of joint.

31
Q

hyper extension of DIP and hyper flexion of PIP

A

boutonniere’s deformity

32
Q

Hallux valgus

A

subluxation of first MTP joint in patients w/o joint pathology. MTP moves laterally due to ligament elasticity. (wearing high heels, female, overweight)

33
Q

Bunion is a protective factor for

A

hallux valgus

34
Q

normal amount of fluid in the knee

A

5ml

35
Q

more than normal(5ml) of fluid in knee can result in

A

hypomobility

36
Q

Never _____ knee joint that has too much fluid

A

move

37
Q

how do you treat a joint with excess fluit

A

remove fluid or take anti-inflammatory drug

38
Q

can’t see hip or knee joint on X-ray

A

aseptic necrosis (due occlusion of blood supply)

39
Q

how do you treat aseptic necrosis of hip joint?

A

replacement

40
Q

Rheumatoid nodules in lungs with pneumonoconious

A

Kaplan’s syndrome

41
Q

RA before age 16

A

juvenile arthritis

42
Q

possible complications of Juvenile RA

A

under developed jaw
early closure of growth plates
anatomical short leg
destruction of dens (can kill them w/c1 adjustment)