more MT stuff Flashcards
anti neutrophil plasmocytic auto antibodies are characteristic of what?
Type III Pauci-immune
What 3 diseases are found with type III pauci-immune?
IGA Nephropathy
Wegener’s Granulomatosus
Poly arteritis Nodosa
vasculitis of vessels with pouching of wall, does not affect the lungs or arch of the aorta
Poly arteritis Nodosa (incurable)
Melting of bones on face that lead to infection
necrotising vasculitis of URT and LRT
terrible smell
Wegener’s Granulematosus
IGA nephropathy aka
Berger’s disease
Usually boys in 20s
hemorrhagic vasculitis
4 syndromes
Henoch Schonlein Purpura (type II Nephritis)
What syndrome of Henoch Scholein Purpura reduces survival rate from 90-70%
Kidney syndrome
2 types of rapidly progressive crescentic Glomerulonephritis
type 1: Anti GBM/ type II HS (goodpasteur’s syndrome)
Type 2: Immune complex deposition/ type III HS
systemic lupus erythematos, henock schonin purpura
Kidney involvement with lupus happens with
UV radiation
Acute pyelonephritis is caused by antibodies against_____ that destroy the ______ wall and is curable with ______
Strep
Glomerular
Corticosteroids
______Cells like the arterioles of the kidney and have _____
endothelial cells
podocytes
hormones of the kidney
renin
erythropoeitin
prostaglandins
if BP drops to ____ then the juxtaglomerular cell will secrete _____
50mg
Renin
BP cascade
renin=>angiotensinogen=>Angiotensin I=>Angiotensin II
acute glomerulonephritis turns chronic in ___ % of children and ___% of adults
1% children
50% adults
what filters the blood
glomeruli
What types of hypersensitivity do the following have?
- Anti-GBM Glomerulonephritis
- circulating immune deposition
- Heyman’s glomerulo nephritis
- type II
- type III
- not a HS reaction
disorders have rapid and progressive dysuria and death w/ in weeks for months
rapidly progressive crescentic glomerulonephritis
subclinical arthritis with pain in joints _____ syndrome
henoch-schonein purpura (articular syndrome)
hemorrhagic inflammation of stomach and duodenal walls _____ syndrome
henoch-schonein purpura (abdominal syndrome)
subcutaneous hemorrhages in legs buttocks and abdomen _____ syndrome
henoch-schonein purpura (cutaneous syndrome)
abdominal, articular and cutaneous syndrome all have a ____% chance of survival reduced to ____% with kidney added
90%
70%
ANA antibody, involves skin, lungs, cerebral vessels, seriouis hypertension, stroke
lupus erythematous
Lupus is type __ rapid crescentic glomerulonephritis and ___ hypersensitiviy
II
III HS
characterized by heavy proteinuria over 3.5g with loss of albumins
nephrotic syndrome
what causes hypoalbuminemia
massive proteinuria
abcess/puss in kidney
development of necrotizing papilitis
WBCs + WBC casts in urinanalysis
problems associated with pylonephritis
supperative inflammation of kidney pelvis and parenchyme
acute pyelonephritis
loss of albumins make the liver produce _____ which lead to ____ and ______
lipoprotiens, hyperlipidemia and lipid uria
loss of _____ causes generalized edema by having the fluid portion excape into tissue responds by producing more ____, this leads to _____
Albumins
Aldosterone
Oliguria
Most common cause of chronic renal failure
chronic pyelonephritis
masangium and pain is muscles is characterisitic of
Berger’s disease (IGA Nephropathy)
Beta hemolytic streptoccoal group A indirectly causes
RF
GMN
antibodies attack layers the heart due to antigens similar to strep
RF
Erythmia annulare, subcutaneous nodules around knuckles, Migratory arthritis, Sydenham chorea
RF
Girls less than 15 y/o
not able to control movement
Sydenham chorea
mitral stenosis leads to ____ sided _____ heart failure
left, congested
_____ atrium is most common for thrombus formation
left (due to mitral stenosis)
Progressive Glomerulonephritis
Anti GMB
Immune Complex
Pauci Immune
Pauci immune
Wegeners Granulomatosis
Polyaritis nodosa
Berger’s disease
instep claudication
HLA antigen
gangrene
Buergers
nerve deafness
catatracts posterior
corneal dystrophy
Alport goes to chronic glomerular nephritis
how many tonsils the pharynx has
6
group A beta hemolytic streptolocci family group
pyogenus
