Pasteurella (Exam 1) Flashcards

1
Q

Pasteurella is a gram (negative/positive) (cocci/rod).

A

gram-negative rod

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2
Q

What is the oxygen requirement for Pasteurella?

A

facultative anaerobe

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3
Q

Pasteurella ferments _______ and _______.

A

glucose
lactose

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4
Q

Which species of Pasteurella affected multiple species, but most commonly young cattle?

A

Pasteurella multocida

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5
Q

Pasteurella multocida causes _________ disease and septicemia in multiple hosts.

A

respiratory

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6
Q

(T/F) Pasteurella multocida is a part of the normal flora in the oropharyngeal tract and only a problem with secondary infections.

A

True

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7
Q

Acute or chronic diseases are associated with (capsulated/non-capsulated) P. multocida, while toxic inflammatory responses are associated with (capsulated/non-capsulated) P. multocida.

A

capsulated
non-encapsulated

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8
Q

________ strain of Pasteurella multocida produces P. multocida toxin (PMT).

A

Type D

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9
Q

Which species of bacteria is not Pasteurella but often grouped with it and also causes respiratory disease often in young cattle and sometimes sheep?

A

Mannheimia haemolytica

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10
Q

Mannheimia haemolytica produces _______ which destroys pulmonary macrophages.

A

cytotoxin

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11
Q

What pathology is seen with both Pasteurella multocida and Mannheimia haemolytica infection?

A

acute, exudative fibrinous pneumonia

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12
Q

(T/F) Mannheimia haemolytica is hemolytic.

A

True

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13
Q

List the two exotoxins of Pasteurella multocida.

A
  1. capsular type D
  2. mitogenic dermonecrotic toxin
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14
Q

List the 2 exotoxins of Mannheimia haemolytica.

A
  1. cytotoxin (leukotoxin)
  2. neuraminidase
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15
Q

Function of neuraminidase in Mannheimia haemolytica.

A

adherence in respiratory tract

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16
Q

What virulence factor of M. haemolytica & P. multocida sensitizes pulmonary endothelial cells for programmed cell death and activates inflammation?

A

endotoxin

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17
Q

(P. multocida/M. haemolytica) have a polysaccharide capsule as a virulence factor.

A

M. haemolytica

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18
Q

(T/F) Food animal strains of Mannheimia haemolytica have multi-drug resistance.

A

True

19
Q

In Sheep, the main causes of Pasteurellosis are M. haemolytica, P. multocida, and ___________.

A

Bibersteinia trehalose

20
Q

(T/F) Therapy is often successful in Pasteurellosis in sheep.

A

False

21
Q

Capsular Type ____ and ____ of Pasteurella multocida are the main cases of Pasteurellosis in swine.

A

A & D

22
Q

Pasteurella multocida Type ___ and ___, cause __________ disease in fowl.

A

A & F
Fowl Cholera

23
Q

Pasteurella multocida which cause Pasteurellosis in dogs and cats are often (capsulated/non-encapsulated) strains.

A

non-encapsulated

24
Q

In rabbits, Pasteurella multocida Type ____ cause Pasteurellosis.

A

A

25
Q

Which two specific rabbit diseases are caused by P. multocida?

A
  1. Snuffles
  2. Enzootic Pneumonia
26
Q

Which rabbit disease causes chronic, mucopurulent rhinitis? Which is often a sequela of the other?

A
  1. Snuffles
  2. Enzootic Pneumonia
27
Q

Pasteurellosis in _______ often shows clinical signs of atrophic rhinitis, purulent bronchopneumonia, and fibrinous pleuritis.

A

swine

28
Q

Which species of bacteria causes Pasteurellosis in lab animals?

A

P. pneumotropica

29
Q

Which species of bacteria, formerly known as a Pasteurella, is an opportunistic organism which causes avian respiratory disease?

A

Avibacterium gallinarum

30
Q

Bovine Respiratory Disease Complex occurs when viral infection downregulates _______ expression of bacterial receptors, so a bacterial infection can occur.

A

TLR

31
Q

Mannheimia haemolytica’s primarily virulence factor is:

A

leukotoxin (LKT)

32
Q

Leukotoxin, used by Mannheimia haemolytica is a type 1 secretion system which has a specific receptor for ___________.

A

alveolar macrophages

33
Q

When ________ lyse M. haemolytica leukotoxin, this puts the body in a pro-inflammatory state.

A

macrophages

34
Q

While a variety of bacteria can cause Bacterial Pneumonia in swine, or PRDC, the major predisposing bacterial species is:

A

Mycoplasma hyopneumoniae

35
Q

Pasteurellosis in dogs and cats is usually found in lesions with Pasteurella _________.

A

multocida

36
Q

While P. multocida is the most common cause of Pasteurellosis in dogs and cats, what other 3 species of Pasteurella may cause the disease?

A

P. canis
P. dagmatis
P. stomatitis

37
Q

______________, secondary to viral infection, occurs in dogs with Pasteurellosis, but is unknown in cats.

A

bronchopneumonia

38
Q

In Pasteurellosis in dogs, ___________ is a common bacterial isolate from bronchopneumonia while in cats it is ____________.

A

Bordetella bronchiseptica
P. multocida

39
Q

What genus is closely associated with Pasteurella, aerobic, a gram-negative rod, and requires special growth factors on artificial media?

A

Haemophilus

40
Q

Which two special growth factors does Haemophilus use for growth on artifical media?

A

x-factor (hemin)
(+/-) v-factor (NAD)

41
Q

Haemophilus is sensitive to which two antimicrobials?

A

ampicillin
tetracycline

42
Q

Where is Haemophilus polyserositis commonly found?

A

nasal cavity of swine

43
Q

Haemophilus paragallinarum commonly affects which species and causes nasal discharge, anorexia, and diarrhea?

A

turkeys

44
Q

Which bacterial organism is responsible for Glasser’s Disease?

A

Haemophilus polyserositis