Pasteurella (Exam 1) Flashcards
Pasteurella is a gram (negative/positive) (cocci/rod).
gram-negative rod
What is the oxygen requirement for Pasteurella?
facultative anaerobe
Pasteurella ferments _______ and _______.
glucose
lactose
Which species of Pasteurella affected multiple species, but most commonly young cattle?
Pasteurella multocida
Pasteurella multocida causes _________ disease and septicemia in multiple hosts.
respiratory
(T/F) Pasteurella multocida is a part of the normal flora in the oropharyngeal tract and only a problem with secondary infections.
True
Acute or chronic diseases are associated with (capsulated/non-capsulated) P. multocida, while toxic inflammatory responses are associated with (capsulated/non-capsulated) P. multocida.
capsulated
non-encapsulated
________ strain of Pasteurella multocida produces P. multocida toxin (PMT).
Type D
Which species of bacteria is not Pasteurella but often grouped with it and also causes respiratory disease often in young cattle and sometimes sheep?
Mannheimia haemolytica
Mannheimia haemolytica produces _______ which destroys pulmonary macrophages.
cytotoxin
What pathology is seen with both Pasteurella multocida and Mannheimia haemolytica infection?
acute, exudative fibrinous pneumonia
(T/F) Mannheimia haemolytica is hemolytic.
True
List the two exotoxins of Pasteurella multocida.
- capsular type D
- mitogenic dermonecrotic toxin
List the 2 exotoxins of Mannheimia haemolytica.
- cytotoxin (leukotoxin)
- neuraminidase
Function of neuraminidase in Mannheimia haemolytica.
adherence in respiratory tract
What virulence factor of M. haemolytica & P. multocida sensitizes pulmonary endothelial cells for programmed cell death and activates inflammation?
endotoxin
(P. multocida/M. haemolytica) have a polysaccharide capsule as a virulence factor.
M. haemolytica