Mycoplasma I & II (Exam 2) Flashcards
Mycoplasma lack a cell wall, so they have no ___________.
peptidoglycan
Mycoplasma have a single walled membrane made of ____________.
cholesterol
(T/F) Mycoplasma are more genetically similar to gram-negative bacteria and stain pink.
False - gram-positive but stain pink (lost peptidoglycan)
Mycoplasma are (facultative/obligate) parasites.
obligate
Mycoplasma are obligate parasites because they cannot make _________ and _________, which they must steal from the host.
pyridines
pyrimidines
How does Mycoplasma appear on culture?
fried egg appearance (small colonies)
(T/F) Mycoplasma is pleomorphic.
True
Mycoplasma makes high levels of what substance which is toxic to eukaryotic cells?
hydrogen peroxide
What is the oxygen requirement of Myoplasma?
facultative anaerobes
Do Mycoplasma have endotoxin? Exotoxins?
No endotoxin
Only 2-3 species make exotoxins
Disease caused by Mycoplasma infection typically causes __________ reactions.
fibrinous
(T/F) Mycoplasma usually infects the GI tract.
False - usually NOT
List 5 common tissues that Mycoplasma infects.
- serous surfaces
- respiratory tract
- mammary glands
- genitals
- circulatory system
Mycoplasma pneumoniae causes what disease in humans, specifically teens?
Primary Atypical “Walking” Pneumonia
Serology is commonly used to diagnose Mycoplasma infection. This is done via what process?
complement fixation
What does a positive complement fixation result mean in a serology test for Mycoplasma?
no RBC lysis (mycoplasma antibodies present)
What does a negative serology result for complement fixation indicate for Mycoplasma?
RBC lysis occurs (no antibodies against Mycoplasma)
In terms of antibiotic treatment, drugs with what mechanism usually work against Mycoplasma?
protein-synthesis inhibitor antibiotics
What 3 major antibiotics is Mycoplasma resistant to due to its structure?
Beta-lactams
Vancomycin
Bacitracin
(T/F) Most Mycoplasma are species-specific.
True
Mycoplasma mycoides subspecies mycoides causes what disease?
Contagious Bovine Pleuropneumonia
In Contagious Bovine Pleuropneumonia, Mycoplasma mycoides subspecies mycoides usually colonizes (one/both) lung(s).
one lung