Mycoplasma I & II (Exam 2) Flashcards

1
Q

Mycoplasma lack a cell wall, so they have no ___________.

A

peptidoglycan

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2
Q

Mycoplasma have a single walled membrane made of ____________.

A

cholesterol

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3
Q

(T/F) Mycoplasma are more genetically similar to gram-negative bacteria and stain pink.

A

False - gram-positive but stain pink (lost peptidoglycan)

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4
Q

Mycoplasma are (facultative/obligate) parasites.

A

obligate

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5
Q

Mycoplasma are obligate parasites because they cannot make _________ and _________, which they must steal from the host.

A

pyridines
pyrimidines

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6
Q

How does Mycoplasma appear on culture?

A

fried egg appearance (small colonies)

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7
Q

(T/F) Mycoplasma is pleomorphic.

A

True

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8
Q

Mycoplasma makes high levels of what substance which is toxic to eukaryotic cells?

A

hydrogen peroxide

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9
Q

What is the oxygen requirement of Myoplasma?

A

facultative anaerobes

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10
Q

Do Mycoplasma have endotoxin? Exotoxins?

A

No endotoxin
Only 2-3 species make exotoxins

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11
Q

Disease caused by Mycoplasma infection typically causes __________ reactions.

A

fibrinous

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12
Q

(T/F) Mycoplasma usually infects the GI tract.

A

False - usually NOT

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13
Q

List 5 common tissues that Mycoplasma infects.

A
  1. serous surfaces
  2. respiratory tract
  3. mammary glands
  4. genitals
  5. circulatory system
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14
Q

Mycoplasma pneumoniae causes what disease in humans, specifically teens?

A

Primary Atypical “Walking” Pneumonia

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15
Q

Serology is commonly used to diagnose Mycoplasma infection. This is done via what process?

A

complement fixation

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16
Q

What does a positive complement fixation result mean in a serology test for Mycoplasma?

A

no RBC lysis (mycoplasma antibodies present)

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17
Q

What does a negative serology result for complement fixation indicate for Mycoplasma?

A

RBC lysis occurs (no antibodies against Mycoplasma)

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18
Q

In terms of antibiotic treatment, drugs with what mechanism usually work against Mycoplasma?

A

protein-synthesis inhibitor antibiotics

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19
Q

What 3 major antibiotics is Mycoplasma resistant to due to its structure?

A

Beta-lactams
Vancomycin
Bacitracin

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20
Q

(T/F) Most Mycoplasma are species-specific.

A

True

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21
Q

Mycoplasma mycoides subspecies mycoides causes what disease?

A

Contagious Bovine Pleuropneumonia

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22
Q

In Contagious Bovine Pleuropneumonia, Mycoplasma mycoides subspecies mycoides usually colonizes (one/both) lung(s).

A

one lung

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23
Q

Contagious Bovine Pleuropneumonia has a (low/high) morbidity and mortality.

A

high

24
Q

(T/F) Mycoplasma mycoides subsp. capri is the most important cause of death in cattle.

A

False (subsp. mycoides)

25
Q

Mycoplasma bovis primarily infects ________ cattle.

A

dairy

26
Q

What disease does Mycoplasma bovis cause in cattle and bison?

A

Severe Epizootic Mastitis

27
Q

List a few clinical signs of Mycoplasma bovis infection (Severe Epizootic Mastitis).

A
  1. polyarthritis
  2. respiratory disease
  3. swollen udders
  4. agalactia (“dry up”)
  5. abnormal milk secretions
28
Q

How is M. bovis transmitted?

A

milking (teat canal)

29
Q

Severe Epizootic Mastitis caused by Mycoplasma bovis can be part of a larger collection of bacterial and viral infections called:

A

BRDC

30
Q

Which two species are affected by Mycoplasma mycoides subsp. capri?

A

sheep & goats

31
Q

What 3 disorders does Mycoplasma mycoides subsp. capri cause?

A
  1. mastitis
  2. polyarthritis
  3. pneumonia
32
Q

Only goats are affected by Contagious Caprine Pleuropneumoniae. Which bacterial species causes this disease?

A

Mycoplasma capricolum capripneumoniae

33
Q

(T/F) Contagious Caprine Pleuropneumoniae is a signficiant disease affected goats populations in the US.

A

False - NOT in US

34
Q

Mycoplasma ___________ causes pneumonia in sheep and caused massive death of “big horn sheep” in the US.

A

ovipneumoniae

35
Q

All Mycoplasma species with the prefix hyo- only affect which species?

A

pigs

36
Q

Which two species of Mycoplasma cause polyarthritis in swine?

A

M. hyorhinis
M. hyosynoviae

37
Q

In addition to polyarthritis, Mycoplasma hyorhinis causes what two other diseases in pigs?

A

polyserositis
pneumonia

38
Q

(T/F) Mycoplasma hyorhinis is in the normal flora of the swine nasal cavity.

A

True

39
Q

Mycoplasma hyosynoviae causing Polyarthritis in swine is (erosive/non-erosive) and therefore, (fibrosis/no fibrosis) occurs.

A

non-erosive
no fibrosis

40
Q

When should you treat for Mycoplasma hyosynoviae (Polyarthritis in swine)?

A

Early! (first 24 hours)

41
Q

Which species of Mycoplasma causes Swine Enzootic Pneumonia?

A

M. hyopneumoniae

42
Q

Mycoplasma hyopneumoniae in pigs has a (high/low) mortality and binds to ________ in the upper respiratory tract.

A

low
cilia

43
Q

As Bordetella bronchiseptica initiates PRDC complex, _________ _________ initiates MIRD complex in swine.

A

Mycoplasma hyopneumoniae

44
Q

What disease is caused by Mycoplasma suis in pigs?

A

Eperythrozoonosis

45
Q

What is the most important avian Mycoplasma species?

A

M. gallisepticum

46
Q

Mycoplasma gallisepticum causes ____________ in chickens and ___________ in turkeys.

A

Chronic Respiratory Disease
Infectious Sinusitis

47
Q

How is M. gallisepticum transmitted?

A

aerosols or transovarian

48
Q

Mycoplasma gallisepticum uses ____________ to turn on and off surface proteins, via phase variation.

A

haemagluttinins

49
Q

Tenosynovitis, arthritis, and respiratory disease, and Eggshell Apex Abnormality in birds are all caused by Mycoplasma __________.

A

synoviae

50
Q

What are the 3 clinical signs are seen in a bird infected with Mycoplasma synoviae?

A
  1. joint lameness
  2. URI
  3. “weakening” of eggshells
51
Q

Which Mycoplasma infects turkeys causing air sacculitis, bone deformities, reduced growth, and genital tract infection?

A

Mycoplasma meleagridis

52
Q

Mice and rats develop chronic respiratory disease by Mycoplasma ___________.

A

Mycoplasma pulmonis

53
Q

(T/F) Mycoplasma pulmonis infection of mice and rats is subclinical until a stressor triggers chronic respiratory disease.

A

True

54
Q

Which Mycoplasma species contributes to Canine Infectious Respiratory Disease Complex in dogs?

A

Mycoplasma cynos

55
Q

Unlike Mycoplasma, the genus Ureaplasma have the enzyme:

A

urease