Parasitology - Nematodes 5 Flashcards
What are the two superfamilies of Spirurida?
Filaroidea
Non-filaroidea
While spirurida is a diverse order and quite difficult to find general characteristics, what do all members have?
an arthropod as an intermediate host
What do spuririda parasitize?
variety of tissues in vertebrate host
Explain the morphology and location of filaroidea
not in GI tract - usually pulmonary arteries
long slender worms
What is the direct host and intermediate host of Spirurida?
arthropods - (mosquitoes are intermediate hosts)
dogs are definitive
What do Spirurida produce?
ovoviviparous - Microfilariae - pre-L1 stage
Explain the lifecycle of heartworm
Mosquito feeds and ingests microfilariae with blood
mosquito matures in infective L3 2 weeks post infection
larvae deposits during subsequent bites
L3 matures into L4 in SC tissue in 1-3 days
L4 larvae migrate through tissues and are sexually immature and migrate to heart and lungs
worms develop to maturity in pulmonary artery
What are the 3 main disease components of Dirofilaria immitis?
physical obstruction of vessels
inflammation in vessel wall
progressive fibrosis in vessel
What disease does Dirofilaria immitis cause?
heartworm
The pathogenesis of Dirofilaria immitis can progress and what happens to the heart?
reduced cardiac output and compensatory right heart enlargement and failure
How is Dirofilaria immitis diagnosed?
HWT annually
microfilaria blood sample check
Explain the role of Wolbachia in Dirofilaria immitis
filarid parasites have a symbiotic relationship with Wolbachia
What medication is being used for treatment of heartworm infection?
Doxycycline
Explain Dirofilaria immitis in cats
abnormal host
worms are less successful and cats show less clinical signs as the worms die soon after infection
and more likely to migrate to abnormal sites
What types of eggs do non-filaroidea superfamilies produce?
clear, elliptical shaped, smooth, thick shell wall containing a coiled larva