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Dealing with Threats > Bacteriology Pasteruellaceae > Flashcards

Bacteriology Pasteruellaceae Flashcards

1
Q

What are the virulence factors that allow for Pasterurellaceae can cause disease?

A

attachment by fimbriae or adhesions
avoidance of phagocytosis with capsules
cellular toxicity with exotoxins
local and systemic effects with endotoxins

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2
Q

Which gram negative bacteria do endotoxins play a greater role in?

A

enterobacterales

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3
Q

What are three negative effects exotoxins can have on a cell?

A

role in atrophic rhinitis
cause lung damage in pneumonia
toxic for phagocytic cells

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4
Q

Being that pasteruellacaea are present as normal flora how is it able to cause disease?

A

opportunistic infections

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5
Q

What host environmental factors contribute to disease development?

A

close quarters
poor ventilation
respiratory virus
young age
poor weather

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6
Q

Explain the pathogenesis of Pasteurellaceae infections

A

NF in respiratory tract
Insult (virus or stress)
bacteria get down into lungs
cause pneumonia

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7
Q

What can occur if different strains of Pasteurellaceae are around?

A

being that they are not part of the NF, they are in carrier animals and are considered to be “better pathogens”

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8
Q

What are some examples of different strains of Pasterurellacae?

A

P multocida capsule type A
P multocida capsule types B and E

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9
Q

Which animal species does P. multocida affect majorly?

A

production animals and companion animals

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10
Q

What are the.4 basic categories of disease associated with Pasturella?

A

pneumonia
rhinitis
bite wounds
septicemia

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11
Q

What is the most important disease caused by Pasteurella?

A

pneumonia

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12
Q

What disease complex is associated with Pasteruella multocida?

A

Bovine Respiratory Disease Complex or Shipping Fever

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13
Q

What does Shipping Fever cause?

A

severe, fibrinous, hemorrhagic, lobar pneumonia causing fibrinopurulent exudate in airways

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14
Q

What is a main factor that causes pneumonia from P. multocida?

A

transportation

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15
Q

What disease does P. multocida cause in rabbits?

A

Rhinitis - snuffles

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16
Q

What does snuffles cause from P. multocida?

A

mucopurulent with fever, nasal discharge, and respiratory distress can develop, septicemia

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17
Q

What is a common disease in pigs caused by P. multocida?

A

Atrophic Rhinitis in young pigs

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18
Q

Atrophic Rhinitis is a combined effect of what two bacteria?

A

Bordetella bronchiseptica allowing P. multocida type D to cause damage

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19
Q

What does B. bronchiseptica cause?

A

initial damage to nasal mucosa allowing P multocida to invade

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20
Q

How is P. multocida type D able to cause Atrophic rhinitis?

A

have a dermonecrotic toxin that causes bone resorption of bony turbinates and suppresses osteoid synthesis adjacent to inflamed area

21
Q

What will you see clinically with Atrophic rrhintis?

A

sneezing
epistaxis
facial distortion

22
Q

How are bite wounds able to cause disease with P.multocida?

A

oral flora which have mixed infections are infected with a cat or dog bite

23
Q

What species can P. multocida cause septicemia in?

A

chickens

24
Q

Are strains of P. multocida that cause septicemia associated with normal flora?

A

NO

25
Q

What 3 diseases does Mannheimia haemolytica cause and in which species ?

A

Pneumonia/bronchopneumonia - Shipping Fever in cattle or enzootic pneumonia in sheep and goats
necrotizing mastitis - ewes
septicemia - lambs

26
Q

What species is Actinobacillus equuli predominant in?

A

horses

27
Q

What 3 diseases does Actinobacillus equui cause?

A

sleepy foal dx - septicemia in neonatal foals
peritonitis in adult horses
pneumonia and pleuropneumonia

28
Q

What disease does Actinobacillus lignieresii cause?

A

wooden tongue in ruminants and is a result of trauma to oral cavity
will see multiple pyogranulomatous abscesses

29
Q

What species is A. pleuropneumoniae predominant in? What are the predisposing factors and what does it cause?

A

PIGS
predisposing factors are crowding, poor ventilation, other infectious agents
causes severe fibrinous pneumonia and pleuritis

30
Q

What is Actinobacillus suis?

A

sepitcemia in pigs 1-8 weeks old

31
Q

What is Glaeserella Parasuis? What species does it effect?What are the two diseases associated with it?

A

PIGS
Bronchosepticemia
Glasser’s disease which causes septicemia and polyserositis which can be caused by stress

32
Q

How does Histophilus somni cause disease and which species is it predominately seen in?

A

cows
invades and disseminates via the bloodstream and produces disease where it localizes causing thrombotic lesions due to exotoxin

33
Q

What three diseases can Histophilus somni cause?

A

Respiratory disease
Thrombotic meningoencephalitis
reproductive failure

34
Q

What disease does Avibacterium paragallinarum cause and in which species?

A

disease in chickens causing inflammation of turbinates, sinus epithelium,, sometimes air sacculitis

causes sneezing and facial swelling

35
Q

How is Pasteruellacaeae grouped?

A

family

36
Q

What are the main hosts affected by P. multocida?

A

cattle, dogs, cats, horses, pigs, sheep, goats, birds, rabbits, humans

37
Q

What are the shared features associated with Pasteurellaceae?

A

gram negative short rods
facultatively anaerobic (but like inc. CO2)
oxidase positive
non-motile
grow on blood agar
variable growth on MacConkey Agar

38
Q

Which Pasterurellacae NOT grow on blood agar? What do these bacteria grow better on?

A

Histophilus, Glaaeserella, Avibacterium
Chocolate agar

39
Q

Which Pasteurellacae NOT grow on MacConkey?

A

multocida, Histophilus somni, Glaeserella parasuis

40
Q

Compared to Enterobacterales, what diseases do Pasteurellacae cause?

A

Broader range

41
Q

Which Pasteurellaceae cause more broad range of infectious disease?

A

Pasteruella, Mannheimia, Actinobacillus, Histophilus

42
Q

Which Pasterurellacaea cause more specific syndromes?

A

Glaeserella and Avibacterium

43
Q

Where do most Pasteurellaceae come from?

A

Normal flora of mucous membranes of animals and birds in the Upper respiratory tracts, digestive tracts, lower genital tract

44
Q

Which Pasterurellaceae cause dx in the upper respiratory tract?

A

P. multifocida, M. haemolytica, Actinobacillus, G parasuis, H. somni

45
Q

Which Pasteurellaceae cause dx in the digestive tract?

A

P. multocida, actinobacillus

46
Q

Which Pasteurellaceae cause dx in the lower genital tract?

A

Actinobacillus suis and H somni

47
Q

While most Pasteurellaceae are part of the normal flora in all animals, some are only present on _____?

A

carriers in upper resp. tract

48
Q

Can Pasteurellaceae survive in the environment for a long time?

A

nope

49
Q

How are Pasteurellaceae transmitted?

A

inhalation, direct inoculation

Dealing with Threats (27 decks)

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