Pantothenic acid (B5)

Question 1

pantothenic acid foods

Answer 1

ALL foods
high in liver, egg yolks, milk

Question 2

pantothenic acid bioavailability

Answer 2

40-60%

Question 3

pantothenic acid is easily destroyed by __ and __ so it is lost in __ foods

Answer 3

pantothenic acid is easily destroyed by heating and freezing so it is lost in processed foods

Question 4

is pantothenic acid safe at high doses?

Answer 4

yes, but very high may cause diarrhea

Question 5

food form of pantothenic acid

Answer 5

coenzyme A

Question 6

pantothenic acid excretion

Answer 6

urine

Question 7

pantothenic acid transporter

Answer 7

SMVT, Na-dependent symporter

Question 8

__% of ingested pantothenic acid is absorbed

Answer 8

50% of ingested pantothenic acid is absorbed

Question 9

absorbable form of PA

Answer 9

pantothenic acid

Question 10

pantothenic acid is not __ prior to excretion

Answer 10

pantothenic acid is not metabolized prior to excretion
excreted intact

Question 11

what is unique about pantothenic acid excretion?

Answer 11

it is excreted intact

Question 12

absorption of pantothenic acid

Answer 12

1. CoA –> PA
2. PA enters enterocyte via SMVT
3. PA sent into portal circulation OR stays in cell and becomes CoA

Question 13

supplement form of PA

Answer 13

pentothenol

Question 14

__ % of ingested PA is absorbed

Answer 14

50 % of ingested PA is absorbed

Question 15

2 biological functions of PA

Answer 15

cofactor in
1. coenzyme A
2. acyl carrier protein (ACP)

Question 16

PA is synthesized in

Answer 16

microbes

Question 17

PA can make

Answer 17

CoA

Question 18

what inhibits PA –> CoA

Answer 18

CoA

Question 19

__ inhibits PA –> CoA, but __ reverses this inhibition

Answer 19

CoA inhibits PA –> CoA, but carnitine reverses this inhibition

Question 20

main function of Coenzyme A

Answer 20

acyl group transfer via ACP

Question 21

ACP function

Answer 21

fatty acid synthesis

Question 22

coenzyme A causes

Answer 22

acyl group transfer

Question 23

assessment of PA status

Answer 23

urinary excretion of PA

Question 24

is PA deficiency common?

Answer 24

it is the rarest

Question 25

people at risk

Answer 25

conditions that increase vitamin need diabetes, alcoholism, bowel disease

Question 26

symptoms of PA deficiency

Answer 26

burning feet syndrome vomiting, fatigue weakness, irritability

Question 27

PA deficiency treatment

Answer 27

calcium-panthothenate

Question 28

what cofactor is needed with PA treatment?

Answer 28

calcium

Question 29

what vitamin deficiency is the rarest?

Answer 29

pantothenic acid it really only occurs as a part of multiple deficiencies