CoQ10 Flashcards
CoQ10 is found in
plant and animal foods
CoQ10 aka
ubiquinon
CoQ10 is __ and __ soluble
CoQ10 is hydrophobic and lipid soluble
CoQ10 is like
a vitamin
CoQ10 is present in __ cells, mainly in __ and __
CoQ10 is present in all cells, mainly in mitochondria and cytosol
CoQ10 main function
transfer of electrons in ETC
cellular respiration
high energy demand = __ conc of CoQ10
high energy demand = high conc of CoQ10
__ is involved in production of CoQ10
HMG-CoA reductase
___ lowers cholesterol by blocking __ which also lowers production of __
statins lowers cholesterol by blocking HMG-CoA reductase which also lowers production of CoQ10
CoQ10 is invorporated into
chylomicrons
VLDL (post-prandial)
LDL
__ enhance absorption of CoQ10 into enterocyte
dietary lipids enhance absorption of CoQ10 into enterocyte
CoQ10 is synthesized endogenously from __
acetyl-CoA
does dietary CoQ10 require a transporter?
NO
dietary CoQ10 is absorbed __ and __ carry it away to cells
dietary CoQ10 is absorbed passively and chylomicrons carry it away to cells
the GI tract __ absorbs CoQ10 bc:
the GI tract poorly absorbs CoQ10 bc:
CoQ10 is large
no enzymes can degrade it