Pancrease Flashcards

1
Q

Pancreatic B cells produce

A

Amylin and insulin

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2
Q

Pancreatic alpha cells secrete

A

Glucagon

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3
Q

Pancreatic D cells secrete

A

Somatostatin

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4
Q

Pancreatic F cells secrete

A

PP

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5
Q

What does amylin do

A

Controls emptying of stomach, saiety, weight loss, inhibits glucagon

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6
Q

What does pancreatic somatostatin do

A

Inhibits segregation of pancreatic hormones (esp insulin), decreases GI motility, stim by glucose and AA

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7
Q

What is the bio marker for pancreatic adenocarcinoma

A

PP

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8
Q

What is used as the indicator for insulin secretion

A

C-peptide

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9
Q

What kind of receptors inhibit insulin

A

Alpha adreneregenic

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10
Q

How does parasymmpathetics increase insulin

A

Arch Stimulates PLC which releases Calcium

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11
Q

What is sulfonylurea used for

A

Type II diabetes, blocks the ATP dependent K leak channel

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12
Q

What transporter does glucose use to enter pancreatic B cells

A

GLT2

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13
Q

What does incretin come From and what does it do

A

GLP-1, GIP, CCK; primes pancreas for insulin release

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14
Q

What does meformin do

A

Stimulates GIP, used to treat type II diabetes

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15
Q

How does dipeptidyl peptides even IV inhibitors work

A

Increase the GLP1 for a longer time, improves glucose tolerance

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16
Q

What does PTP do

A

Terminates signal of insulin receptor

17
Q

What is the effect of insulin on lipoprotein lipase and FA synthase

A

Increases both

18
Q

Insulin and light exercise increase the expression of

A

GLUT-4

19
Q

Chronic stress and intense exercise induces

A

Hyperglycemia

20
Q

GH, cortisol, and glucagon are all

A

Ketogenic

21
Q

What are the stimulators of glucagon

A

Hypoglycemia, AA, NE, EPI

22
Q

Glucagon is inhibited by

A

Insulin, somatostatin, FA

23
Q

Glucagon uses what pathway

A

G protein

24
Q

What is the effect of hyperkalemia on insulin release

A

Increases insulin release