Male Repro Phys Flashcards
GnRH cell bodies are located
Arcuate and medial preoptic
What would you give to prevent puberty in a developing 6 yr old
Constant GnRH, desensitizes receptors
T/F sex steroids directly mediate CnRH
False, they act indirectly
Progesterone inhibition of GnRH pulse freq is antagonized by
Androgens
Androgen insensitivity has what effect on LH
Increases
What is the effect of high DHT on LH
DHT decreases LH
What it’s the effect of estrogen and progesterone on GnRH
When together they decrease GnRH
What does activin do
Stimulate FSH, secreted by S and L
What does inhibin do
Inhibits FSH, secreted by serotoli cells
What does follistatin do
Binds to activin, dissactivating it, secreted by Sertoli cells
Stress ______ GnRH
Inhibits
Melatonin _________ GnRH
Suppresses
Leptin _________ GnRH
Increases
LHR, FSHR has what kind of signaling cascade
cAMP
LH, FSH, TSH share
A common a chain
Be able to draw thing
Do it
What does CYP19A1 do
Converts testosterone to estradiol
What closes the epiphyseal plates
Estrogen
Where is AMH produced
Sertoli cells
While Sheehan or kallman be distinguishable at birth
Sheehan; both are hypogonadism
What is hypergonadotrophic hypogonasism
High LH and FSH, low testosterone
What cells create the blood-testis barrier
Sertoli
What gives sexual sensation (nerve)
Spinal reflex
Where are sperm stored, concentrated, and gain motility
Epididymis and ductus deferens
