Adrenal Cortex Flashcards

1
Q

What deficiency has hyponatremia, hyperkalemia, dehydration, and hypotension

A

Aldosterone

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2
Q

What defieiciency has hypoglycemia and hypotension

A

Cortisol

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3
Q

What deficiency has lack of puberty in females

A

DHEA

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4
Q

What transports cholesterol in miso mem

A

StAR

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5
Q

What converts cortisol to cortisone

A

11B-HSD1

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6
Q

Where are MR found

A

Distal nephron

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7
Q

Aldosterone has a ______ half life and is carried by ______

A

Short; CBG

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8
Q

What are the effects of aldosterone

A

Increase sodium retention, K and H+ excretion

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9
Q

BC and pregnancy increase

A

CBG, more total cortisol

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10
Q

glucocorticoids are highest in the

A

Morning

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11
Q

What are the effects of cortisol

A

Insulin def, lipolysis, protein catab

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12
Q

Does severe adrenal hyperlasia make you hypo or hypertensive

A

Hypo

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13
Q

What are the non met problems with high cortisol

A

Low lung mat, Na retention, increase osteoclasts, striae

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14
Q

Cushing syndrome is associated with high

A

ACTH

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15
Q

Hypoglycemia, hypotension anorexia, and fainting are associated with

A

GC def

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16
Q

Hypoglycemia, hypotension, anorexia, fainting

A

GC def

17
Q

How does cortisol injections lead to lowering inflammation

A

Blocks phospholipase A2, lowers leukotrienes and prostaglandins (IL2, TNFa, NFkB)