Pance endocrine round 2 8/15 Flashcards by sean husted

where is CRH produced and what effect does it have

hypothalamus

- produce more ACTH

How well did you know this?

Not at all

Perfectly

what is the location of a primary disorder

at the gland level

How well did you know this?

Not at all

Perfectly

what effect does an adrenal adeonoma have on cortisol

increase

How well did you know this?

Not at all

Perfectly

anti thyrogloblin antobody what pathology

hashimotos

How well did you know this?

Not at all

Perfectly

thyroid stimulating antibodies what pathology

graves

How well did you know this?

Not at all

Perfectly

what are the three meds you give for a thyroid storm

PTU
Beta blocker
Glucocorticoids

How well did you know this?

Not at all

Perfectly

thyroid brui think what

graves

How well did you know this?

Not at all

Perfectly

what is the MC type of thyroid nodules

follicular adenoma

How well did you know this?

Not at all

Perfectly

how often do you monitor a thyroid nodule with US

every 6- 12 months

How well did you know this?

Not at all

Perfectly

what is the MC type of thyroid cancer

papillary

How well did you know this?

Not at all

Perfectly

what is another name for Vit D

Calcitrol

How well did you know this?

Not at all

Perfectly

what is the MC cause of hyperparathyroidism

patrathyrois adnenoma

How well did you know this?

Not at all

Perfectly

what are the DTR with hypercalcemia

decreased

How well did you know this?

Not at all

Perfectly

what are the DTR with hypothroid

decreased

How well did you know this?

Not at all

Perfectly

what are the 2 MCC of hypoparathyroidism

surgery

- autoimmune

How well did you know this?

Not at all

Perfectly

what are the 3 big physical exam signs of hyperparathyrod hormone

trousseau’s
chvosteks
Increased DTR

How well did you know this?

Not at all

Perfectly

how do you tx hypoparathyroidism

Ca gluconate

- Vit D

How well did you know this?

Not at all

Perfectly

what part of the EKG is effected by calcium

QT interval

How well did you know this?

Not at all

Perfectly

hypocalcemia what effect of QT

long

How well did you know this?

Not at all

Perfectly

3 tx for hypercalcemia

saline
fursemide
bisphosphenates

How well did you know this?

Not at all

Perfectly

inc PTH and hypocalcemia what pathology

renal osteodystrophy

How well did you know this?

Not at all

Perfectly

brown tumors

- salt pepper on X ray skull

renal osteodystrophy

How well did you know this?

Not at all

Perfectly

how do you tx riskets

vit D (ergocalciferol)

How well did you know this?

Not at all

Perfectly

what kidney disease has too much phosphate

renal osteodystrophy

How well did you know this?

Not at all

Perfectly

how do you tx renal osteodystrophy 2

- phosephate binders | - sevelamer

what gland produces ACTH

pituitary

what is the main cause of chronic adrenocortico insufficiency (primary: addisons, Secondary: pituitary)

Secondary: pituitary

what is the 2 main primary adrenocortico insufficiency (addiosns caused)

- autoimune | - infection

what is the main secondary adrenocortico insufficiency

- exogenous steroid use

what are the 4 metabolic disorders associated with addidosns

hyponatremia hypoglycemia hyperkalemia metabolic acidosis

how do you tx primary adrenocortico insufficiency

hydrocortisone + fludrocortisone

how do you tx secondary adrenocortico insufficiency

hydrocotisone

what is the cause of addisons criss

abrupt withdrawl of glucocorticoids

how do you tx adisosn crisis

- IV fluids | - hydrocortisone, fludrocortisone

what is the metabolic cause of cushings disease

- Increased ACTH

what is the potassium change with cushings

- hypokalemia

what is the cause of cushings disease

- pituitary ademonia (secretes ACTH)

what are the two main tests for cushings

- 24 hr free cortisol in urine | - dexamethasone supression

how do you tx a cortisol secereting ACTH tumor

ketoconazole

how do you tx cushings diease

- transphenodial surgery

what are the two causes of hyperaldosteroneism

- Conn syndrome | - renal artery stenosis

catacholaime secreting tumor

- Pheo

what are the symptoms of pheo

- palpitations - headache - excessive sweating

how do you dx a pheo

- 24 hr catacholamine collection

how do you tx pheo

- complete adrenalactomy

what medication do not not start with when tx a pheo

- beta blocker

what hormones are secreted by the posterior puitary

- ADH | - Oxytocin

what hormone is a prolactin agonist

- dopamine

what two medications are dopamine agomist

- cabergoline | - bromocriptine

how do you tx acromegaly

octreotide

what hormone is produced with somatotropinoma

growth hormone

what are the two presentations of hyperprolactinemia

- ammenorrhea | - galactorrhea

what are the four medications that cause gyncomyastia

Spironalactone cematadine ketoconazole finesteride

what is the fasting glucose level for DM

126

what are the two causes of DKA

infection | non compliance with insulin

what element do you always give with DKA

postassium

where is the problem with cushings disease

-pituitary

what 2 meds are anti thyroid

- MME | - PTU

what are the 3 tx for graves

- iodine - MME / PTU - Beta blockers

what is the MCC of hyperparathyroidism

parathyroid adenoma

what are the 3 P with MEN

parathyroid pancreius puititary

what MEN is associated with pho

- MEN 2

3 tx for HYPERcalcemia

- Fluids - fursemide - bisphosphenates

1 tx for HYPOcalcemia

- calcium gluconate

what are the DTR with HYPERcalcemia

decreased DTR

what is the DTR with GBS

decreased

DTR with Hyperthyroid

increased

``` what are - trousseau's - chvosteks - Increased DTR associated with ```

HYPOcalcemia

Flat T waves | U waved

HYPOkalemia

peaked T waved

HYPERkalemia

what are the 3 tx for HYPER-Kalemia

- calcium gluconate (stabilized the membrane) - Insulin - albuterol

what adrenal insufficiency disorder still produces aldosterone and why

secondary because secondary is with the pituary and this means ACTH is not produced however aldosterone will be produced with the kidney

aldoderone is what type of corticoid

mineral corticoid

what is an eg of a mineral corticoid

fludrocortizone

weight gain hypokelemia acanthosis nigracans

cushings

what are the three endogenous causes for cushings

- cushings disease (puitary adenoma) - ectopic ACTH - adrenal tumor

test for cushings

dexamenthaosne supression

test for adisons

ACTH stimulation

how do you tx acromegaly 2 meds

- bromocriptine | - Octreotide

what are the two subjective reports for prolactin tumor

- amenorrhea | - galactorrhea

prolactin tumor tx 2

carbogaline | bromocriptine

4 meds that cause gyncomaystia

- spironalactone - Finesteride - cematatide - ketoconazole