PAIN LECTURE Flashcards
An unpleasant sensory and emotional
experience, which we primarily associate
with tissue damage or describe in terms of
such damage, or both (IASP, 1994;
Ranney, 2008).”
The fifth vital sign
pain
Melzack and Wall (1965) emphasized the
importance of the central nervous system
mechanisms of pain
gate control model
Peripheral nerve endings stimulated by
source of pain which transmit the sensations
to the central nervous system.
nociceptors
types of stimuli
mechanical
thermal
chemical
types of physiologic process in nociception
transduction
tranmission
modulation
perception
results in tissue injury or
damage stimulating the
nociceptors
transduction
initiate
painful stimulus resulting in inflammatory
process to release of cytokines and
neuropeptides
noxious stimuli
Initiated by this
inflammatory process,
resulting in the conduction
of an impulse in the
primary afferent neurons
to the dorsal horn of the spinal cord
transmission
Inhibits pain message and
involves the body’s own
endogenous
neurotransmitters in the
course of processing the pain stimuli
modulation
Inhibits pain message and
involves the body’s own
endogenous
neurotransmitters in the
course of processing the pain stimuli
perception
this controls body
temperature during stress
diaphoresis
this causes
elevation in blood pressure with shift of
blood supply from the periphery and
viscera to the skeletal muscles and brain
peripheral vasoconstriction
this causes blood supply to shift
away from the periphery
pallor
this results from fatigue
muscle tension
this causes the
body defenses to fail under prolonged
stress of pain
rapid, irregular breathing
Pain elicits a stress response in the human
body triggering the sympathetic nervous
system resulting in
physiologic responses
classification of pain
acute pain
chronic nonmalignant pain
cancer pain
this is usually associated with
a recent injury
acute pain
this is
usually associated with a specific cause or
injury and described as a constant pain
that persists for more than six months so
an example is back pain
chronic nonmalignant pain
This is often due to the
compression of peripheral nerves or
meninges or from the damage to these
structures following surgery,
chemotherapy, radiation therapy, or
tumor growth and infiltration
cancer pain
classfication pf pain location
cutaneous pain
visceral pain
deep somatic pain
is usually on the skin or
subcutaneous tissue
cutaneous pain
usually in the abdominal
cavity thorax and cranium
visceral pain
usually in the ligaments tendons bones
blood vessels and nerves
deep somatic pain
Can be perceived in
nerves left by a missing amputated or
paralyzed body part
phantom pain
causes an abnormal
processing of pain messages and results
from past damage to peripheral or
central nerves due to sustained
neurochemical levels. Exact mechanisms for
the perception of neuropathic pain are
still unclear
neuropathic pain