Paget's Disease (Osteitis deformans)

Question 1

A disorder of localized rapid bone turnover, most commonly affecting the skull, femur, tibia, pelvic bones, and vertebrae

Answer 1

Paget’s Disease (Osteitis deformans)

Question 2

2% - 3% of the population older than 50yrs of age

Slightly greater in aging men than in women

Answer 2

Paget’s Disease (Osteitis deformans)

Question 3

A chronic disease in which the bones gradually becomes thick and also soft, causing them to bend

Family history is noted

Answer 3

Paget’s Disease (Osteitis deformans)

Question 4

A type of bone cell that removes bone tissue by removing its mineralized matrix and breaking up the organic bone (organic dry weight is 90% collagen)

Answer 4

Osteoclast

Question 5

An osteoclast, a type of bone cell that removes bone tissue by removing its mineralized matrix and breaking up the organic bone (organic dry weight is 90% collagen)

This process is known as __________

Answer 5

Bone resorption

Question 6

A cell from which the bone develops; a bone-forming cell

Answer 6

Osteoblast