Osteomalacia: Clinical Assessment

Question 1

Osteomalacia: Clinical Assessment

Answer 1

1. X-ray = generalized demineralization of bone is evident
2. Studies of the vertebrae may show a compression fracture
3. Bone biopsy demonstrates an ↑osteoid

Laboratory studies
1. ↓Serum calcium and phosphorus

2. Moderately ↑alkaline phosphatase concentration
3. ↓urine excretion of Ca and creatinine

Question 2

The unmineralized, organic portion of the bone matrix that forms prior to the maturation of bone tissue

Answer 2

Osteoid