(P4) Resp Pathos: Tuberculoma

Question 1

Identify:

Macro appearance* and what *organs

does this lesion affect?

Answer 1

Tuberculoma

Macro:

-Firm, round tumor (not neoplastic) (benign)

-Solitary mass with central caseous necrosis surrounded by granulomatous tissue

-Encapsulated

Affects:

Lung, meninges (brain)

Question 2

When can Tuberculoma form?

Answer 2

Turberculoma can form when treating tuberculosis.

• If treatment stops, new granuloma forms around healing areas (fibrotic areas).
• Up to 10 cm. Looks like malignant tumor

NOTE: In tumor with central necrosis, need to check border to determine cell type to differentiate from

neoplasm

Question 3

INDENTIFY:

Micro:

Answer 3

Tuberculoma

• Part of slide pink, other area darker. Large, light pink area = necrosis.
• Many new small granuloma around large area of necrosis.
• Epithelioid cells (elongated nucleus).
• Can be layers of necrosis mixed with layers of fibrosis.

Question 4

Identify :

Answer 4

Tuberculoma

Question 5

Identify:

Answer 5

Tuberculoma