(P4) Resp Patho: Fibrocaseous tuberculosis of the lung Flashcards
Identify
![](https://s3.amazonaws.com/brainscape-prod/system/cm/336/883/216/q_image_thumb.png?1613762160)
Fibrocaseous tuberculosis of the lung
![](https://s3.amazonaws.com/brainscape-prod/system/cm/336/883/216/a_image_thumb.png?1613762232)
1. epithelioid cells*
2. Langhans Giant cells*
- mycobacterium tuberculosis
- The combination of parenchymal lesion and nodular involvement. The Ghon complex undergoes fibrosis and detectable calcification
- granulomatous inflammation
IDENTIFY SLIDE
What causes this lesion
and
how is it transmitted?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/336/883/320/q_image_thumb.png?1613762270)
Fibrocaseous tuberculosis of the lung
Caused by mycobacterium tuberculosis
- Inhaled M. tuberculosis is deposited in the alveoli, usually in the lower and middle lobes and
anterior segments of upper lobes.
-Generally transmitted from person to person by aerosolized droplets
![](https://s3.amazonaws.com/brainscape-prod/system/cm/336/883/320/a_image_thumb.png?1613762334)
Identify this slide:
What type of lesion is this
and
what type of Cells are primarily found?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/336/883/403/q_image_thumb.png?1613762701)
Fibrocaseous tuberculosis of the lung
Caseous granuloma – classic lesion of TB
-Soft, semisolid core surrounded by epithelioid cells*, *Langhans giant cells, lymphocytes and peripheral fibrous tissue
▪ Caseous necrosis in center:
–>This is why this form of TB is called fibrocaseous TB
![](https://s3.amazonaws.com/brainscape-prod/system/cm/336/883/403/a_image_thumb.png?1613762666)
Describe the Gross appearance and Microscopy
of
Fibrocaseous tuberculosis of the lung
![](https://s3.amazonaws.com/brainscape-prod/system/cm/336/883/781/q_image_thumb.png?1613762826)
- Gross:*
- Large nodule (white, chalky appearance), caseous necrosis. Granuloma at the edge
- Slide:*
- Edges of necrosis fibrosis (fibrous connective tissue surrounds granulomas). Lesions are large
(unlike in military tuberculosis)
![](https://s3.amazonaws.com/brainscape-prod/system/cm/336/883/781/a_image_thumb.png?1613762848)
Identify:
![](https://s3.amazonaws.com/brainscape-prod/system/cm/336/883/982/q_image_thumb.png?1613762972)
![](https://s3.amazonaws.com/brainscape-prod/system/cm/336/883/982/a_image_thumb.png?1613762999)
Identify:
![](https://s3.amazonaws.com/brainscape-prod/system/cm/336/884/060/q_image_thumb.png?1613763030)
![](https://s3.amazonaws.com/brainscape-prod/system/cm/336/884/060/a_image_thumb.png?1613763056)
Identify :
![](https://s3.amazonaws.com/brainscape-prod/system/cm/336/884/101/q_image_thumb.png?1613763091)
Fibrocaseous tuberculosis of the lung
![](https://s3.amazonaws.com/brainscape-prod/system/cm/336/884/101/a_image_thumb.png?1613763118)