(P4) Cardiac: Uremic cardiomyopathy

Question 1

Identify Slide:

Answer 1

Uremic cardiomyopathy

Question 2

• Uremic cardiomyopathy*
• What type of Cardiomyopathy is it?*

Answer 2

Type of secondary cardiomyopathy

• Dilated, hypertrophic or rarely restrictive*
• • Four‐chamber hypertrophy and/or dilatation are evident*
• • Most muscle cells are hypertrophied with enlarged nuclei, but some are attenuated, stretched, and irregular*
• • Interstitial and endocardial fibrosis of variable degree is present*

Question 3

Uremic cardiomyopathy

Uremia forms due to what condition and resulting in what?

Answer 3

Uremia in chronic renal failure

Failure of renal excretory function, metabolic and endocrine alteration in renal damage

Fibrinous or serofibrinous pericarditis

Fibrin layer on surface of pericardium

Cardiomyopathy

Question 4

• Uremic cardiomyopathy*
• Leads to?*

Answer 4

Leads to enlargement of cardio myocardium

Note: If without known cause – primary

• Some causes of disease:* uremia, alcoholic
• Normal heart around 300-350 grams.*

With cardiomyopathy can weight up to 900 grams.

Question 5

Uremia

Answer 5

• Cardio myofiber becomes larger, split ends, irregular distribution–Fiber scars at split ends of myocardial fibers of myocardium
• Increase in interstitial tissue
• Whole myocardium is enlarged–Enlarged myocardium usually develop clinical insufficiency

Question 6

Answer 6

Question 7

Answer 7

Question 8

Identify

Answer 8

Question 9

Identify

Answer 9

Uremic cardiomyopathy