Ovarian Cancer Flashcards

1
Q

what is it difficult to diagnosis

A

by the time it is detected 75% have metastasized already
and no suitable screening test
and advances silently
= most lethal female CA

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2
Q

ET/Risk factors

A
aging
ovulatory age
family hx (breast CA)
autosomal dominant 
nulliparity
dysmenorrhea 
infertility
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3
Q

why is age a risk factor

A

it increases your likelihood of expose to carcinogens

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4
Q

what is ovulatory age

A

the time that oocytes are exposed to sex hormones

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5
Q

Patho what are the diverse types

A

epithelial tissue is most prevalent
then germ cells
and stromal tumors

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6
Q

how does ovarian cancer advance

A

silent growth
seeds (bowels and liver)
and extends

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7
Q

as it grows it causes what

A

pressure on adjacent organs

and abdominal distention

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8
Q

how does ovarian metastasize

A

via blood and lymph

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9
Q

Manifestations of ovarian CA

A

early non specific GI manifestations
abdominal distention
pain
urinary and bowel obstruction

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10
Q

what is a complication that arises from these manifestations

A

ascites and dyspnea

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11
Q

what is usually the first finding

A

pelvic mass but usually too late at this point

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12
Q

when a pelvic mass is found what occurs

A

US

and exploratory surgery (laproscopy)

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13
Q

Treatment is determined how

A

by the exploratory surgery which you repeat again 6-24 months

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14
Q

Treatment

A

aggressive: surgery to remove ovaries, tubes, uterus, omentum
chemo
some can recover fully!

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