Glomerulonephritis Flashcards

1
Q

what is glomerulonephritis

A

glomerular inflammation (always preceded by an infection)

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2
Q

Proliferative GN is also known as

A

acute post infectious GN

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3
Q

is this common?

A

yes

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4
Q

what infection is ace post infectious GN preceded by

A

beta hemolytic strep infection

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5
Q

what does this infection do

A

causes hemolysis of the blood, usually in the pharynx and the skin

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6
Q

where does this infection mostly occur

A

in children with a 95% recovery rate

- in adults this infection 30% leads to renal failure

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7
Q

What type of HS is it

A

type 3 HS

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8
Q

what occurs in a type 3 HS

A

an ABAG complex is formed (immune complex) and is unable to be broken down - gets trapped in the glomerulus - filtration is impeded
macrophages come and destroy - large holes for unwanted molecules to get in

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9
Q

what are 2 characteristics of APIGN

A

hypercellularity
- leukocytes, mesangial cells, endothelial cells
glomerular enlargement
- related to inflammation

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10
Q

What initially happens and then changes to what?

A

oliguria which leads to proteinuria and hematuria (gets through large holes from destruction)

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11
Q

you will see and increase in what two lab values

A

BUN And creatinine

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12
Q

this increase in indicative of what?

A

azotemia

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13
Q

a retention of what two things will lead to what two things

A

h20 and Na retention leads to HTN and deem (decrease osmolarity from decrease in proteins)

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14
Q

Treatment

A

mostly self limiting

symptomatic management

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