Cervical Cancer Flashcards

1
Q

what is the part that becomes malignant

A

the walls of the cervix

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2
Q

Etiology/risks

A

HPV
-strains 6/11 cause genital warts
strains 16/18 account for cervical cancer

Early age sex
multiple partners
smoking
HX of std

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3
Q

Patho: how does the malignancy progress

A

in a widening fashion

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4
Q

what type of cell origin is cervical cancer

A

squamous cell origin

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5
Q

there is an initial WHAT That occurs

A

dysplasia (pre cancer lesion)

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6
Q

later on that dysplasia then…

A

becomes invasive into the deeper tissue layers (years between pre cancer stage and invasive stage)

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7
Q

what does CIN stand for

A

cervical intraepithelial neoplasia

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8
Q

what are the levels of cervical intraepithelial neoplasia

A

CIN1: mild dysplasia
CIN2: moderate
CIN3: severe and carcinoma in situ

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9
Q

how does cervical cancer metastasize

A

via lymphatics

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10
Q

Diagnosis

A

Screening tool: PAP smear to see if squamous cells have changed in appearance *dysplasia
colposcopy if dysplasia is present

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11
Q

Manifestations

A
vaginal discharge
bleeding
metrorrhagia 
frequent menses
late: pain
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12
Q

Treatment

A
early: excision of the cells undergoing dysplasia
Invasive: radiation and surgery
Cryosurgery
Conization
Laser: bring about necrosis
Advanced: radical hysterectomy
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