other anti-inflammatory Flashcards
1
Q
JAK inhibitors indications
A
- rheumatoid arthritis
- crohns disease
- leukemias
- alopecia
2
Q
oclacitinib indications
A
atopic dermatitis
3
Q
common cause of atopic dermatitis
A
commonly from flea bites - saliva of fleas
4
Q
JAK inhibitors pharmacological effects
A
- antiinflammatory
- antiallergic
- antipruritis
5
Q
JAK inhibitors absorption
A
excellent per os absorption, 90%
6
Q
JAK inhibitors absorption with food
A
no difference
7
Q
JAK inhibitors metabolism
A
liver
8
Q
JAK inhibitors interactions
A
no interactions with other drugs
9
Q
JAK inhibitors side effects
A
no major, but sometimes causes vomiting
10
Q
lokivetmab specificity
A
highly specific
11
Q
other allergy mediated diseases
A
- atopic dermatitis
- cutanous food adverse reactions
- FAD
12
Q
are antihistamines antagonists
A
no, theyre inverse agonists
13
Q
the two forms of histamine receptors
A
active and inactive
14
Q
antihistamines usage
A
- individual differences
- allergic diseases
- asthma, RAO
- anaphylactic reaction
15
Q
how many generations of antihistamines
A
2
