Orofacial Infection Flashcards
T/F Candida can be isolated from
Healthy mouths?
T
What is the most common type of fungal oral mucosal infective agent?
Candida albicans
What are local factors which predispose to oral candidiasis?
Denture wearing at night
Dry mouth
Steroid therapy esp inhaled
High carb diet
How can candida be categorised?
Acute
Chronic
What systemic factors predispose to or candidiasis?
Immunocompromised T cell defects (HIV, diabetes,leukaemia) Age extreme AB therapy Diabetes mellitus Anaemia
What are examples of acute candida ?
Acute pseudo membranous candidiasis
Acute erythmatous/strophic candidiasis
Name examples of chronic candidal infection?
Chronic hyperplastic candidiasis (leukoplakia )
Chronic erythmatous candidiasis (denture stomatitis)
Candida associated lesion:
Angular chelitis
Median rhomboid glossitis
Mucocutaneous candidiasis
How does oral thrush present?
White patches on the oral mucosa which are easily removed by rubbing off may leave mucosal erythema
A disease if a disease
Seen in neonates which haven’t yet developed immunity
What microbiological tests can be performed with people that babe candidiasis?
Swab: culture and sensitivity testing
Phosphate buffered mouthwash: not site specific
What tests can be done for thrush?
Correct any local or systemic cause
Check FBC/B12/folate/blood glucose and HIV tests
Microbiological
How do you threat thrush?
Topical: MAN
Systemic: for Immunocompromised or where wide spread lesions
What is another name for chronic hyperplastic candida?
Candidal leukoplakia
How does candidal leukoplakia
Present?
Non remove able white lesion on commissaries of buccal mucosa
Frequently
Bilateral
Typically seen in smokers
How do you diagnosis CHC?
Clinicslly BUT need histopathology confirmed
How do you manage CHC?
Manage risk factors
Topical AF
Systmic AF
Follow up long term since malignancy risk of 9-40
How does acute erythematous candida present?
Erythmatous area
What are the risk factors for acute erythmatous candida?
Steroid inhalers and AB
What is another name for denture stomatitis?
Chronic erythmatous candida
How do you treat acute erythmatous candid?
Topical AF
rinse mouth after steroid inhaler
How does chronic erythmatous candida present?
Usually on palate with upper surface of denture it is often a symptomatic
How do you treat chronic erythmatous candida?
Topical AF therapy and denture hygiene
What is an example of a candida associated lesions?
Median rhomboid glossitis
Angular chelitis
How does median rhomboid glossitis present?
Lobulated lesion at junction between post and anterior tongue
It is usually asymptomatic
And dx is clinical
Topical AF therapy needed
What is a less common bacterial infectjon of the mouth?
Alveolar abscess/cellulitis
name some bacterial infections of the mouth?
ANUG Osteomyelitis Periaplical abscess Periodontal abscess Periocoronitis Infected cyst
What is the difference between alveolar abscess and cellulitis ?
Abscess is collection of pus
Cellulitis diffuse pus
Which spaces can infection spread in head and neck?
SM space SL space Submental space Mental space Buccal space Canine/infraorbital space Submasseteric space Pterygomandibular space Deep temporal space Superficial temporal space
Where does infection from upper centrals drain?
Labial
Nasal cavity if long roots
Where does infection from upper 2’s spread?
Palate
Where does infection from
Upper canines spread?
Labial sulcus or infraorbital
Where does infection from maximal let posterior teeth drain?
Buccal sulcus due to thin buccal place and high attachment of buccinator
Where do lower incisors point?
Since mentalis attaches above apices, it usually drains at chin point or submental space
Where do mandibular molars drain to?
If apices are above Mylohyoid then sublingual
If below Mylohyoid then submandibular
Where do periodontal abscesses drain to?
Via gingival sulcus or laterally
Which bacteria are commonly imbued in periodontal abscesses?
Gram neg anaerobes eg PG/ fusobacteria
spirochete sand actinomyces
What agents are involved in ANUG?
Poly microbial
Anaerobes
Boriella vincentii
Fusobacteria nucleatum
What predisposes you to ANUG?
Poor OH Smoking Immunocompromised Stress Vit C def Viral resp infections
What key features relate to ANUG?
Halitosis
Loss of interdental papilla
Slough
Pyrexia?
How do you treat ANUG?
Metronidazole 400mg tds
What are the potential risks of untreated dental infections?
Osteomyelitis Cellulitis Fistula formation Septacaemia Spread into tissue spaces Meningitis
Which organisms are associated with CST?
Staph aureus
What is cavernous sinus thrombosis?
Formation of blood clot in Cavernous sinus
What can predispose to CST?
Nasal infection 50% Sinus infection (30%) Dental infection (10%)
What is osteomyelitis ? And how can it be classified?
Inflammation of the bone marrow
Suppurative
-acute suppurative osteo
-chronic suppurative osteo
non suppurative
- diffuse sclerosimg
- focal sclerosimg
- proliferative periostitis
- ORN
What are the symptoms of CST?
Palpebral oedema Cyanosis Exophthalmos Proptosis Dilated pupil Limited eye movement Rigors Pyreixa
What are the sources of osteomyelitis?
Periaplical or peridontal infection
Fractures
Penetrating injuries
What are the predisposing factors for osteomyelitis?
Osteoradionecrosis
Osteopetrosis
What are the signs and symptoms of osteomyelitis ?
Deep seated throbbing pain Sweeping Halitosis Anorexia Parasthesia Malaise Fever Cervical lymphadenopathy Tooth mobility Pus Leukocytosis
What causes syphylis?
STI
Treponema palladium
What are the sequelae following infection with T Pallidium?
Primary syphylis: primary chancre at site of inoculation following oral sex, causes painless ulcer and lymphadenopathy
Secondary : snail track ulcers 2-6 weeks later
Terriary: leukoplakia and gumma on palate
What causes TB?
Mycobacterium Tuberculosis
How do you treat syphylis?
Benzathine pencillin for 1 month
Oral lesions are rare in TB? T/F
T
How may TB present in Head and neck?
Ulcer on dorsal of tongue
Salivary gland swelling
Lymphadenopathy
How do you treat TB?
Rifampicin
Isomiazid
Ethambutol
Spiramycin
How do oral lesions in TB develop in mouth?
Tubercle bacilli in sputum coughed into mouth
What is erysipelas?
Acute streptococcal infection which spreads via lymphatic system
Usually caused by strep pyogenes which produced exotoxin and then rash
What is actinomycosis?
Chronic supportive infection which is rare. Swelling at angle of the mouth
Multiple sinus formation and trimsus and caused by gram pos organisms, a israelli and aa
Tropical country
What signs indicate acinomycosis?
Extra oral sinus with no oral cause
May occur following jaw surgery or neck
What are the demographics associated with actinomycosis?
30-60 male
When does a israelli become pathogenic?
When tissue is non vital and reduced oxygen
How do you treat actinomycosis?
Pencillin
Drainage
What are the 5 of infective periodontal diseases?
Linear gingival erythema NUG NUP ANUG Cancrum oris
What is the agent involved in Linear Gingival Erthema?
Fungus
Which bacteria are involved in acute ulcerative gingivitis?
Spirochete and fusiform
They invade muscle
What happens to the tissue in AUG?
Gross oedema which spreads outwards destroying soft tissues and bone
Why do the tissues slough away in AUG?
Because gangrenous infection occurs leading to loss of teeth and necrotic sequestra
In what demographics is AUG mainly seen in?
Children under 10 Immunocompromised Protein deficiency Anaemia Poor OH Systemic infection eg measles
What can AUG lead to?
Cancrum oris
Which fusiform bacteria are involved in Cancrum oris?
Porphyromonas
Fusiform necrophorum
Boriella vincentii
How can viral infections be diagnosed?
In the lab
Clinically