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Oral Med > Lupus > Flashcards

Lupus Flashcards

1
Q

What are the types of Lupus?

A

discoid

systemic

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2
Q

What is systemic lupus erthmatosis?

A

this is a multisystem immune complex disorder
more commonly seen in black and asian middle aged
more commonly seen in females

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3
Q

What parts of the body are affected in SLE?

A

mutlisystem
organs: kidney, lungs, joints, heart, brain
Mucosal tissues

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4
Q

What immunological features do the blood tests show in SLE?

A

RF (30%)
hypergammaglobunaemia
hypocomplemetnamia
AntiDNA (90%)

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5
Q

What is the type of lupus which only affects the skin?

A

discoid

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6
Q

What percentage of the time do you see oral lesions in DLE?

A

25%

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7
Q

Where do the immune complexes become lodged in SLE?

A

in the vessels

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8
Q

What are the antibodies in SLE against?

A

dsDNA

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9
Q

What is the effect of the immune complexes in the kidney?

A

Leads to nephrotic syndrome and kidney failure

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10
Q

What is the effect of the immune complexes on the heart and lungs?

A

Endocarditis, pneuminitis, epicarditis, pericardidits

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11
Q

What is the effect of immune complexes in joints?

A

arthralgia and arthrits

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12
Q

What is the effect of the immune complexes on the skin?

A

butterfly rash and lichen planus type lesions

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13
Q

WHat percentage of people with SLE suffer fro eye problems?

A

25%

retintits and conjuctivits

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14
Q

How do you manage SLE?

A

bipody and bloods

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15
Q

What type of histopathoology analysis do you do for the bipsied tissues?

A

fixed tissue: histopath

frozen tissue: DIF

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16
Q

How do you treat SLE?

A

steroids,NSAIDS, topical, immunosupressants, anti malarials

17
Q

What does the serolgy for DLE show?

A

normal

18
Q

How do you control DLE?

A

topical steroids

19
Q

What are the symptoms of lupus?

A 
Lymphadenopathy 
Parasthesia
Raynauds
Oral ulceration 
Chest pain

Oral Med (31 decks)

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