ORIGIN AND DEVELOPMENT OF ORGAN SYSTEM Flashcards
4 days of life zygote cells are termed TOTIPOTENS STEM CELLS (undifferentiated cells) and has potential to grow into any cell in the human body
next 4 days embryo cells begin to show differentiation
few more days and they specifically grow into a particular body organ
i. stem cells
as soon as conception takes place, development proceeds in a cephalocaudal direction
ii. zygote growth
(outermost layer): develops into the nervous system, the integumentary system, the sense organs, and mammary glands
ectoderm
(middle layer): develops into supportive structures of the body: connective tissue, bone cartilage; kidney and urethra; reproductive system; heart, lymph, circulatory systems, and blood cells)
mesoderm
(innermost layer): develops into the lining of the gastrointestinal and respiratory tracts as well as the tonsils, thyroid, parathyroid, and thymus glands. Also develops the lower urinary system (bladder and urethra)
endoderm
by the end of 8th week gestation all organ systems are complete; vulnerable to invasion of teratogens (cigarette smoking and alcohol ingestion)
organogenesis (organ formation)
one of the first systems to become functional in intrauterine life
iv. circulatory system
network of blood vessels and single heart tube is formed
16th day of life:
positive heartbeat;
24th day:
septum that divides hearts into chambers develops
6th-7th week:
heartbeat may be heard by using a doppler instrument
heart rate of the fetus is affected by: oxygen level activity and circulating blood volume
10th-12th week
sympathetic nervous system matures and the heart rate stabilizes (normal HR: 110-160 bpm)
28th week:
fetus is connected by umbilical cord to the placenta
through the blood vessels in the umbilical cord, the fetus receives all the necessary nutrition, oxygen, and life support from the mother through the placenta
waste products and carbon dioxide from the fetus are sent back through the umbilical cord and placenta to the mother’s circulation to be eliminated
fetal circulatory system uses two right to left shunts (2 shunts in the heart and 1 shunt in the lungs) (small passages that direct blood that needs to be oxygenated.) purpose of these shunts is to bypass certain body parts in particular, the lungs and the liver that are not fully developed while the fetus is still in the womb
the shunts that bypass the lungs are called the foramen ovale, which moves blood from the right atrium of
the heart to the left atrium while the ductus arteriosus moves blood from the pulmonary artery to the aorta;
v. fetal circulation
respiratory and digestive tract exists as a single tube
3rd week of intrauterine life:
septum begins to divide the esophagus from the trachea and lung buds appear on the trachea
end of 4th week: