Oral Path: Salivary Gland-Reactive/Benign/Malignant Flashcards
Mucous Extravasation Phenomenon
Cause: Salivary Duct Trauma
* not a true cyst
Mucocele:
* Lower Lip
* Salivary Duct blocked due to trauma
Ranula:
* Floor of mouth
tx: COMPLETE excision of minor gland
* Ranula=Sublingual Gland
Mucous Retention Cyst
Cause: Sialolith blocks salivary duct
* True Cyst
Necrotizing Sialometaplasia
Rapidly expanding ulcerative lesion
Cause: ischemic necrosis of minor salivary glands
* due to trauma or local anesthesia
Tx: Palliative
* heals on its own in 6-10 wks
Sinus Retention Cyst
Aka Antal Pseudocyst
Cause: Salivary Glands blocked in sinus mucosa
Tx: None
Sarcoidosis
Hyperimmune
* involves granulomas
Triggers:
* Mycobacteria (same as TB)
Primarily a pulmonary disease
* but also affects salivary glands & muosa
* Causes XEROSTOMIA
Tx: Corticosteroids
Sjogren’s Syndrome
Autoimmune & lymphocyte mediated
* Affects salivary & tear glands
Types:
Primary:
* Keratoconjunctivitis sicca (Dry eyes)
* + Xereostomia
Seconary:
* Primary + another autoimmune disease (Rheumatoid arthritis)
Tx: Symptomatic
Pleomorphic Adenoma
Most common Benign Salivary gland tumor
comoppsed of:
* mixture of cell types: epithelial & CT
* why its AKA Mixed tumor
Firm rubbery swelling:
Most common site:
* minor salivary gland=palate
* parotid gland=ear
Monomorphic Adenoma
Benign Salivary Gland tumor
Composed of: 1 type of cell
Includes:
* basal cell adenoma
* canalicular adenoma
* myoepithelioma
* oncocytic tumor
tx: Surgical excision
Warthin’s Tumor
Benign Salivary Gland Tumor
Composed of:
* Oncocytes(Cells w/XS Mitochondria)
* Lymphoid cells
Most common: Parotid Gland of Older Men
Mucoepidermoid Carcinoma
Most common Salivary Gland Malignancy
composed of:
* Mucous
* epithelial cells
Polymorphous Low-Grade Adenocarcinoma (PLGA)
2nd most common Salivary Gland malignancy for minor glands
Adeno=gland
Adenoid Cystic Carcinoma
Malignant Salivary Gland Tumor
Cribiform or Swiss cheese microscopic pattern
5 year survival=70%
15 year=10% Very Lethal
