Oral Path: CT-Benign & malignant Tumors

Question 1

Fibroma

Answer 1

aka Traumatic Fibroma, Irritation Fibroma, Hyperplastic scar

Fibrous hyperplasia of oral mucosa
* Cause: Chronic Trauma or irritation

Question 2

Gingival Hyperplasia

Answer 2

aka Gingival Enlargement
CDC concerned about Gingival Hyperplasia

Calcium Channel Blockers:
* Nifedipine
* Amlodipine
* Verapamil

Dilantin: Anticonvulsant/epileptic

Cyclosporine: Immunosuppressant

Tx: Gingivectomy and discontinue drug if possible

Question 3

Dentur-Induced Fibrous Hyperplasia

Answer 3

Epulus Fissuratum:
* Base of vestibule
* Cause: Overextended flange of denture

Papillary Hyperplasia:
* hard palate
* cause: Poor denture hygiene

(Angular Cheilitis)

Question 4

Traumatic Neuroma

Answer 4

Entangled submucosal mass of:
* neural tissue
* scar

Cause: Nerve Injury
* most common=mental foramen (Mental N.)

Question 5

Multiple Endocrine Neoplasia

Answer 5

aka MEN 2B

=Multiple Neuromas (not traumatic)

+ medullary thyroid Cancer

+ Pheochromocytoma of adrenal gland

Question 6

Pyogenic Granuloma

Answer 6

Hyperplasia of capillaries=RED color

Cause:
* Chronic trauma or irritation

Gingiva=most commn

Question 7

Nodular Fasciitis

Answer 7

Neoplasm of Fibroblasts

easy to eradicate (Opposite of Fibromatosis)
* Rare recurrence

Tx: Excision

Question 8

Fibromatosis

Answer 8

Neoplasm of fibroblasts

Difficult to eradicate (opposite of nodular fasciitis)
* high Recurrence

Question 9

Granular Cell Tumor

Answer 9

Neoplasm of Schwann Cells

Contain:
* granular cytoplasm
* Pseduoepitheliomatosu Hyperplasia (PEH)-mimics SCC histologically

Dorsal tongue=Most common

Congenital Epulis of Newborn
* variant
* on gingiva
* no PEH

Question 10

Schwannoma

Answer 10

aka Neurilemmoma

Neoplasm of Schwann Cells

Acellular Verocay bodies in Antoni A Tissue
* Forms a line of scrimmage

Question 11

Neurofibroma

Answer 11

Neoplasm of Schwann Cells and Fibroblasts

Question 12

Neurofibromatosis type I

Answer 12

Aka Von Recklinghausens Disease (Von FRECKLINGhuasen Disease)

=Multiple Neurofibromas

+ Multiple skin freckles (Cafe au lait spots)

+ Axillary Freckles (Crowe’s sign)

+ Iris freckles (Lisch spots)

neurofibromas can transform to neurofibrosarcomas

Question 13

Leiomyoma

Answer 13

Neoplasm of smooth muscle cells

Question 14

Rhabdomyoma

Answer 14

Neoplasm of skeletal muscle cells

Question 15

Lipoma

Answer 15

Neoplasm of fat cells

buccal mucosa=most common

Question 16

Fibrosarcoma

Answer 16

Malignant Proliferation of fibroblasts

Question 17

Neurofibrosarcoma

Answer 17

aka Peripheral Malignant nerve sheath tumor

Malignant proliferation of Schwann Cells

Question 18

Kaposi’s Sarcoma

Answer 18

Malignant proliferation of endothelial cells

cause: HHV8 (Human Herpes Virus 8)
* Hard Palate
* most commonly seen as complication in AIDs pt

Purple Lesion

Question 19

Leiomyosarcoma

Answer 19

Malignant proliferation of smooth muscle cells

Question 20

Rhabdomyosarcoma

Answer 20

Malignant prolifeation of Skeletal Muscle cells

Question 21

Liposarcoma

Answer 21

Malignant proliferation of Fat cells