Oral epithelium and connective tissue Lecture 4/5

Question 1

these are examples of what

• Collagen fibre
• Elastic fibre
• Capillary
• Fibroblast
• Hyaluronan, proteoglycans and glycoproteins
• Mast cell
• Macrophage
• Basal lamina

Answer 1

connective tissue

Question 2

…………………………….is defined as any supporting tissue that lies between other tissues and consists of cells embedded in a relatively large amount of extracellular matrix. Includes, bone cartilage and loose connective tissue.

Answer 2

connective tissue

Question 3

there are a few cells within the connective tissue, which cell is present at the greatest concentration

Answer 3

fibroblasts

Question 4

A common cell type found in connective tissue. …………. secrete an extracellular matrix rich in collagen and other extracellular matrix macromolecules. Migrates and proliferates readily in wounded tissue and in tissue culture.

Answer 4

fibroblast

Question 5

can fibroblast act as stem cells

Answer 5

yes

Question 6

………………….. can be defined as- a complex network of polysaccharides (such as glycosaminoglycans or cellulose) and proteins (such as collagen) secreted by cells. Serves as a structural element in the tissues and also influences their development and physiology

Answer 6

extracellular matrix

Question 7

what is the function of extracellular matrix

Answer 7

support for cells

Question 8

depending on the pattern of extracellular matrix, it can regulate the following:

Answer 8

polarity

cell division

adhesion

motility

Question 9

……………………rare chronic disease characterized by excessive deposits of collagen growth factors

(name the disease)

Answer 9

Scleroderma

Question 10

……………………chronic debilitating and precancerous caused by chewing – increase in type 3 and then type 1 collagen.

Answer 10

oral submucosa fibrosis

Question 11

what causes osteogenesis imperfecta - brittle bones

Answer 11

insufficient collagen

Question 12

rare genetic disorder caused by defect in collagen synthesis. Symptoms include unstable, flexible joints- skin and tendons easily stretched.

condition is called

Answer 12

Ehler’s Danlos syndrome

Question 13

what is scurvy

Answer 13

a deficiency disease lack of vitamin C- needed for hydroxylation proline to hydroxyproline.

Question 14

…………………………An increase in the number of cells; as a result of cell growth and cell division.

Answer 14

cell proliferation