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GI II Exam 1 > Oral Cavity Path II > Flashcards

Oral Cavity Path II Flashcards

1
Q

oral hairy leukoplakia

A

immunosuppression and EBV

lateral border of tongue

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2
Q

lateral tongue, white, doesn’t scrape

A

oral hairy leukoplakia

**do an HIV test

balloon cells

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3
Q

balloon cells

A

oral hairy leukoplakia

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4
Q

black hairy tongue

A

poor hygiene
-don’t scrape off and debride surface of tongue

tobacco, coffee, tea

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5
Q

rash with ampicilin

A

mononucleosis

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6
Q

monospot test

A

neurophile antibodies - for EBV

-mono test

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7
Q

other mono test

A

mix serum from patient with sheep/horse RBCs

  • EBV - creates heterophile antibodies
  • positive - agglutination of RBCs - clumping
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8
Q

mononucleosis

A

hyperemic mucosa - posterior pharynx

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9
Q

irritation fibroma

A

bite line - tongue or mucosa
-repetitive trauma

reactive fibroblast tissue

tx - surgical excision

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10
Q

pyogenic granuloma

A

gingiva, tongue
-pregnancy tumor

reactive granulation tissue

  • benign inflammatory vascular lesion
  • may bleed

common in young people

tx - surgical excision

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11
Q

pregnancy tumor

A

pyogenic granuloma

granulation tissue

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12
Q

cancer of oral cavity

A

95% SCC
5% adenocarcinoma of salivary glands

tobacco and alcohol

india - chew betel quid and paan

oral pharynx - type 16 HPV

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13
Q

posterior pharynx cancer

A

HPV - 16 and 18

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14
Q

anterior mouth cancer

A

tobacco

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15
Q

cells pass BM

A

metastasis

need biopsy to determine lesion is malignant

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16
Q

leukoplakia

A

white patch/plaque
-cannot be scraped off

due to increased keratin

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17
Q

hyperkeratosis

A

not premalignant change

bx needed

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18
Q

erythroplakia

A

red patch

  • less common than leukoplakia but more ominous
  • 90% dysplasia or CIS

highly vascular eroded mucosa

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19
Q

keratin peral

A

squamous cell carcinoma

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20
Q

oral SCC

A

80% are stage II/III with high rate of recurrence

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21
Q

stage 3 and 4 SCC

A

always radiation

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22
Q

CIS SCC of oral cavity

A

treated like stage 1 - primary surgery/ radiation

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23
Q

five hear survival stage 1/2 SCC

A

70-90%
-need careful follow up

increased risk of second head and neck cancer as well as lung ca

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24
Q

wide local excision

A

oral cavity cancers

25
Q

transoral laser resection

A

oropharynx, hypopharynx, larynx

26
Q

strawberry tongue

A

scarlet fever

27
Q

koplik spots

A

measles

28
Q

acute pharyngitis and tonsillitis - gray white exudative membrane

A

infectious mono

29
Q

wartons duct

A

submandibular gland

-gleeking

30
Q

salivary glands

A

parotid - serous
submandibular - mixed
sublingual - mixed

31
Q

minor salivary glands

A

lubrication

-buccal, gingival, palatal mucosa

32
Q

acute b/l tender swelling of parotid and salivary glands lasting 2 days

A

mumps

-virus

33
Q

mumps complication

A

testicular inflammation - orchitis

sterility may occur

34
Q

parotitis

A

swelling of parotid gland
-mumps

may last up to 10 days

35
Q

mumps vaccine

A

MMR

third dose - in outbreak setting

contraindication - pregnant, immunosuppressed, malignancy

36
Q

sjogrens syndrome

A

third most common autoimmune
-female age 40yo

autoAbs agasinst Ags in salivary glands and lacrimal glands

37
Q

keratoconjunctivitis and xerostomia

A

sjogrens

dry eyes and dry mouth

38
Q

sicca syndrome

A

dry eyes and mouth

-sjogrens

39
Q

severe sjogrens

A

risk of NHL

40
Q

diagnosis of xerostomia

A

bx of salivary gland

-see lymphocytes attacking glands

41
Q

sjogrens association

A

rheumatoid arthritis

SLE, polymyositis, scleroderma, vasculitis, thyroiditis

42
Q

blurry vision, itchy, dysphagia, dry mouth, inabilty to taste

A

sjogrens

43
Q

SS-A titers

A

extraglandular sjogrens disease - synovitis, pulmonary fibrosis, peripheral neuropathy

more likely to have early disease onset and longer duration as well

44
Q

mikulicz syndrome

A

lacrimal and salivary gland enlargement from any cause

45
Q

sjogrens dx

A
  • biopsy
  • CD4 T cells ans B cells
  • rheumatoid factor - IgG
  • ANAs on immunofluorescence
  • SS-A and SS-B
46
Q

mucocele

A

msot common lesion of salivary gland - mucous retention cyst

block of salivary gland tract

often lower lip**

tx - excision - if incomplete - recurrence occurs

47
Q

sialolith

A

blockage of salivary duct - food particle = nidus

enlargement with aggregation of dehydrated mucous

often submandibular gland

48
Q

bacterial sialadenitis

A

unilateral duct obstruction causes stasis

allows infection - staph aureus or strep viridans

acute inflammation - to chronic inflammation

49
Q

benign tumors of salivary gland

A

pleomorphic adenima - mixed

warthin tumor

50
Q

malignant tumor of salivary gland

A

mucoepidermoid carcinoma

adenoid cystic carcinoma

51
Q

pleomorphic adenoma

A

mixed tumor- benign
-of salivary gland

50% of all tumors of salivary gland

epithelial and mesenchymal cells
-arise from basal myoepithelial cells

52
Q

epihelial and myxoid tumor

A

pleomorphic adenoma of salivary gland

can be left in place

15 years - 10% develop to malignant

53
Q

painless slow growing mobile discrete mass in submandibular/buccal area

A

pleomorphic adenoma

54
Q

warthin tumor

A

papillary cystadenoma lymphomatosum

10% salivary tumors, benign
-males, 50-60yo, smokers**

55
Q

warthin tumor bx

A

double layer of eosinophilic epithelial cells over lymphoid stroma*

56
Q

malignant tumors of head and neck

A

adenocarcinoma
mucoepidermoid carcinoma
adenoid cystic carcinoma

57
Q

mucoepidermoid carcinoma

A

parotid

  • malignant
  • slow growing

grade important for px

  • high grade - invasive
  • low-hrade - rare mets

mucicarmine stain - for mucin

and pink sqamous epidermoid cells

58
Q

adenoid cystic carcinoma

A

malignant of salivary gland

infiltrate along nerve**
-perineural invasion

recurrent common

swiss cheese appearance - holes

GI II Exam 1 (29 decks)

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