Liver Path VII Flashcards
cholestasis in pregnancy
pruritis during the third trimester
conjugated bile
focal nodular hyperplasia
solitary lesion
- common in liver
- not neoplasm**
-is a congenital vascular anomaly
with osler weber-rendu disease
malformation of vessels in liver parenchyma - hyperperfusion occurs
excess O2 causes hyperplasia - forms nodule
most common b9 non-vascular hepatic mass
focal nodular hyperplasia
commonest hepatic tumor
cavernous hemangioma
central scar
seen in focal nodular hyperplasia
Tc99-SC
nuclear scan
sulfur colloid taken up by kupffer cells
for focal nodular hyperplasia
diagnosis also shows central stellate scar
cavernous hemangioma
bleed like crazy - don’t stick needle in it
hepatic adenoma
b9 tumor of liver in young women taking oral contraceptive
RUQ pain and large lesion
males - with anabolic steroids
subcapsular - prone to rupture
don’t biopsy - bleeding
resect if > 5cm
hepatocellular carcinoma
very common with HBV
background of cirrhosis from any cause
also small risk in Hep C
abundance of alpha-fetoprotein
alpha-fetoprotein
very high in hepatocellular carcinoma
fetal form of albumin
aflatoxin
africa
from aspergillus
hepatocellular carcinoma
diagnosis of hepatocellular carcinoma
need biopsy
fibrolamellar variant
of hepatocellular carcinoma
young males and females
single large hard mass
infiltrating tumor cells with background of desmoplasia
no association with hep B, hep C, or cirrhosis
vinyl chloride
with angiosarcoma
tumor of blood vessels
mets to liver
more common than primary liver tumor
nearly always multiple
common cause of death in other cancers
