GI Path CIS Flashcards

1
Q

dilantin

A

can develop gingival hyperplasia

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2
Q

sjogrens

A

more cavities

but no gingivitis

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3
Q

tzanck test

A

for multinucleated giant cells

and intranuclear inclusions
-of virus particles

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4
Q

biting lip lesion

A

irritating fibroma

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5
Q

PAS stain

A

candidiasis

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6
Q

herpes

A

has blisters

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7
Q

won’t scrape off

A

oral hairy leukoplakia

-EBV infection

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8
Q

will scrape off

A

candidiasis
PAS

pseudo-hyphae

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9
Q

perineural involvement

A

adenoid cystic carcinoma

spreads along nerves

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10
Q

friable and readily bleed

A

can be in tumors

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11
Q

pyogenic granuloma

A

readily bleeds

  • women
  • pregnancy
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12
Q

smoking and teeth

A

brown discoloration

-into tubular structures into teeth

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13
Q

ameloblasts

A

create enamel

stop when gets above gum

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14
Q

tetracycline

A

bind to calcium

contraindicated in pregnancy
-2 and 3 trimester - ameloblasts putting enamel to dentin

discoloration yellow - to gray/black - of teeth

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15
Q

lots of pink eosinophilic change in cytoplasm

A

keratin
-squamous epithelium

squamous cell carcinoma

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16
Q

omphalocele

A

can be associated with overreactive pancreas

also - beckwith wiedemann syndrome

17
Q

presentation of meckel diverticulum

A

like appendicitis

or GI bleed

18
Q

meckel diverticulum

A

defect in viteline duct obliteration

usually asymptomatic

gastric mucosa detection 99mTc

19
Q

herpes

A

nuclear inclusions

can occur in esophagus

20
Q

double bubble

A

annular pancreas

duodenal atresia

21
Q

hirschsprungs

A

aganglionosis

finger in butt - POOP!

22
Q

metaplasia

A

replacement of cell

23
Q

nitrous oxide

A

can induce odd chained fatty acids

-deficit of succinyl CoA incorporated into myelin

24
Q

gastrinoma

A

zollinger-ellison

severe gastritis can occur

and dyspepsia

25
Q

cocaine

A

lower GI bleed

26
Q

false positive guiac

A

eat meat - blood from meat causes guiac positive

27
Q

upper GI bleed above ligament of trietz

A

in contact with acid

-melena - black tarry stool

28
Q

kaposi sarcoma

A

oral cavity

  • red lesion, slightly elevated
  • acid-fast positive organisms

latent herpes infection

29
Q

regional lymph nodes for colon

A

pericolonic adipose tissue

30
Q

colon ca to brain

A

to arterial circulation

  • to vein through liver
  • through lungs
  • through heart
  • to brain
31
Q

colon mets to liver stop where?

A

sinusoids

maybe to the space of disse

cells adhere to endothelium

32
Q

paraneoplasm with colonic adenocarcinoma

A

nephrotic syndrome - membranous glomerulopathy - immune complexes auto-Abs against antiphospholipase A2 reeptor

also:

venous thrombosis

some say none

33
Q

membranous glomerulopathy

A

nephrotic syndrome

proteinuria**

antiphospholipase A2 recpetor Abs

need biopsy for diagnosis

34
Q

groin nodes

A

below dentate line

- anus

35
Q

HPV

A

anal SCC

viral E6/E7 oncogenic proteins

36
Q

PiZZ

A

homozygous alpha-1 antitrypsin deficiency

misfolded protein accumulation

37
Q

black liver

A

dubin johnson syndrome

inability to secrete conjugated bilirubin

deposition of epinephrine metabolites

38
Q

PBC

A

destruction of bile ducts

39
Q

<1cm bile duct

A

intra-hepatic