Ophthalmology: Cornea Flashcards
Describe the anatomy of canine conjunctiva?
- Thin mucous membrnae
- Lines the lids reflected at the dorsal and ventral fornices onto the globe
- Covers nicitating membrane
- Contains globles cells- mucus fraction of tear
- What is the normal colour of mucus from the conjunctiva?
- What colour does it change to with conjunctivitis?
- Off-white, darkens to grey with air
- Yellow/green
- What are primary causes of non-specific conjunctivitis?
- How is it usually treated?
- Wind, dust, trauma- oppertrunistic
- Fusidic acid- effective against staphs or broad spec AB (gentamycin)
If persist look for another factor
What produces the tear film in the dog?
Three layers
* Mucus- globlet cells of the conjunctiva
* Aqueous- lacrimal gland/nicitating membrane
* Lipid- tarsal glands
- What is KCS or Dry eye?
- What are the clinical signs?
- Keratoconjunctivitis sicca- deficiency of aqueous tear film production
- Clinical signs
* Loss of corneal reflex
* Corneal ulceration- acute
* Superficial keratisis
* Corneal pigmentation
* Diffuse conjunctivitis
* Mucopurulent occular discharge
Most are chronic and progressive
What breeds are represented for KCS?
What can cause it?
- WHWT
- Cocker
- Brachycephalics
- Bulldogs
Upper lid trichiasis, congenital, neurogenic
How is KCS diagnosed?
How is it medically managed?
Diagnosis
* Schirmer tear test strips
* Measure flow over 1min
* 15mm minimum
Medical managment
* Tear stimulants- cyclosporin or tarcolimus
* Lubricants
- What is dry eye-dry node syndrome?
- How is it treated?
- One eye and ipsilateral nasal planum suffer loss of gland function- neurogenic
- Pilocarpine eye drops in food
How do tears drain?
Naso-lacrimal duct- near the medial canthus
How are tear drainage problems investigated and diagnosed in dogs?
- Rule out painful causes of lacrimation
- Examine medial canthus for entropion
- Establish normal nasolacrimal puncta
- Instil 1 drop of fluorescein into both eyes
- Flush with saline and wait
- 3-4 mins should flow into nares
- Flush system- sedate, lacrimal cannula
Brachys negative- weird
What are common causes and treatments of tear drainage problems?
Congenital micropuncta
* Golden retriever, cocker spaniel
* Thin membrane- excised
Dacryocysitis- infection/inflammation of duct from FB
Epiphora- permanent opstruction- bypass surgery
What are the 4 layers of the cornea?
What innervates the cornea?
- Outer epithelium- needs tears
- Stroma- consisting of fine collagen fibrils arranged in lamellae- precise arrangment
- Descemets membrane- acellular basemend membrane
- Endothelium- monolayer of flat cells
Opthalmic branch of trigeminal
What is required for the normal cornea to be transparent?
- No keratin
- No pigment
- Avascular
- Precise arrangment of collagen in stoma- no oedema, scar tissue, inflammatory tissue
What is a corneal ulcer?
A full thickness defect in the epithelium of the cornea- outermost layer
Very painful- potential for deeper progression
How is corneal ulcer diagnosed?
- Corneal contour is disrupted often with surrounding oedema
- Fluorescein- washes of intact, stains exposed