Ondansetron

Question 1

What are the 4 actions of ondansetron

Answer 1

1. Potent seretonin 5HT reception antagonist
2. Precise mode of action unknown, likely to have actions both peripherally and on the CNS
3. Max effect 10 mins post IV admin
4. Hepatic metabolism

Question 2

What is the use of ondans?

Answer 2

Prevention or treatment of nausea and vomiting

Question 3

What are the 6 adverse effects of ondansetron?

Answer 3

1. Headache
2. Flushing of skin
3. Occasional reaction at site of injection
4. Drowsiness
5. Anxiety and agitation
6. Transient visual disturbances

Question 4

What is the precaution for ondansetron?

Answer 4

Not recommended in pregnancy

Question 5

What is the adult dose of ondansetron?

Answer 5

4mg slowly over 2 minutes. May be administered IM if necessary. Repeat once if required after approx 10 mins

Question 6

What is the paediatric dose of ondansetron?

Answer 6

100mcg/kg (to a max of 4mg) slowly over 2 minutes. May repeat once after 10 minutes if required. May be given IM if necessary