GTN (Anginine)

Question 1

What type of drug is GTN

Answer 1

Nitrate smooth muscle relaxant and vasodilator

Question 2

What is the presentation of anginine tablets

Answer 2

600mcg tablets

Question 3

what are the actions of anginine

Answer 3

1. Arterial and venous vasodilation

2. Dilation of collateral coronary vessels

Question 4

What are the uses for GTN

Answer 4

1. Relieve cardiac pain of ischaemic origin
2. Pulmonary oedema
3. Autonomic dysreflexia

Question 5

What are the 4 adverse effects of GTN?

Answer 5

1. Hypotension
2. Headache
3. Flushing of skin
4. Occasionally -reflex bradycardia or tachycardia

Question 6

What are the 6 contraindications of GTN?

Answer 6

1. BP < 90
2. HR < 50
3. Viagra or Levitra within 24 hours
4. Cialis in 4-5 days in elderly or 3-4 days in all other patients
5. KSAR
6. ^ ICP

Question 7

What are the notes of admin on GTN?

Answer 7

1. Pt should be sitting so bottle is upright
2. Prior to each use prime spray
3. Instruct pt to close mouth after admin and do not swallow or inhale
4. Following each use alcho wipe. If significantly contaminated, discard

Question 8

How soon should GTN Tablets be used?

Answer 8

3 months of opening bottle. Tablets should fizz if still potent

Question 9

What is the dose for chest pain for both tablet and spray. Include max dose

Answer 9

Tablet- 1 tab may repeat once if necessary. Half tab (300mcg) if pt has never had GTN before or BP between 90-100mmHg

Spray- 1 x spray max 4 doses. 5 mins between dose

Question 10

What is the max dose of GTN sprays for APO?

Answer 10

3 doses

Question 11

What is the max dose for GTN spray for autonomic dysreflexia?

Answer 11

3 doses

Question 12

What is the adult and paed anginine tablet dose for autonomic dysreflexia?

Answer 12

1/2 tab (300mcg) adult

1/4 tab (150mcg) paed (12-16yrs)