Ondansetron Flashcards

1
Q

Ondansetron

Class

A

Anti-emetic

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2
Q

Ondansetron

Description

A

Used in the management of nausea & vomiting.

Potent, highly selective 5HT3 receptor-antagonists

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3
Q

Ondansetron

Presentation

A

Ampoule 2ml (4mg in 2ml)

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4
Q

Ondansetron

Administration

A

Intravenous (IV)

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5
Q

Ondansetron

Indications

A

Management, prevention and treatment of significant nausea and vomiting

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6
Q

Ondansetron

Contraindications

A

KSAR

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7
Q

Ondansetron

Dosage

A

Adult: 4mg slow IV
Paed: 0.1mg/Kg IV slowly or IM to Max 4mg

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8
Q

Ondansetron

Pharmacology

A

Precise mode of action in the control of nausea & vomiting is not known

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9
Q

Ondansetron

Side Effects

A

Headache
Sensation of warmth
Flushing
Injection site reactions (Rash, Itching, Urticaria)

Uncommon:
Arrhythmias
Bradycardia
Hiccups
Hypotension
Seizures
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10
Q

Ondansetron

Additional Info

A

Caution in patients with a known Hx or FMHx of cardiac conduction intervals (QT prolongation) or if patient has a Hx of arrhythmias or electrolyte imbalance

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