Methoxyflurane

Question 1

Methoxyflurane Class

Answer 1

Anaesthetics: General: Volatile Anaesthetic Agent

Question 2

Methoxyflurane Presentation

Answer 2

3ml vial with a tear off tamper evident seal which is administered via carbon inhalation vapouriser

Question 3

Methoxyflurane Administration

Answer 3

Inhaled (Inh) through an activated Carbon Chamber (Self administered)

Question 4

Methoxyflurane Indications

Answer 4

Moderate to severe pain

Question 5

Methoxyflurane Contra-indications

Answer 5

<5 years old
Altered LOC due to head injury, drugs or alcohol
Cardiovascular instability
Respiratory Depression
Renal Failure or Impairment
Ksar
Malignant Hyperthermia

Question 6

Methoxyflurane Dose

Answer 6

Adult & Paed: 3ml (Inh) (rpt x1 only)

Question 7

Methoxyflurane Side Effects

Answer 7

Amnesia
Anxiety
Depression
Dizziness 
Dysarthria
Dysgeusia (Distortion of sense of taste)
Euphoria
Headache
Sensory Neuropathy
Somnolence
Hypotension
Coughing
Dry Mouth
Nausea
Feeling Drunk
Sweating

Uncommon:
Tingling or Numbness to hands and feet
tiredness
mouth discomfort

Question 8

Methoxyflurane Additional Info

Answer 8

Patients with pain due to ACS or migrane may not be suitable for Methoxyflurane.
Methoxyflurane crosses the placenta. Consider the risk of CNS and respiratory depression in an already compromised foetus.
Methoxyflurane has a mildly pungent odour.
If used in a confined space request the patient to inhale and exhale through the inhaler tube while ensuring that the activated Carbon Chamber is attached