Magnesium Sulphate Injection

Question 1

Magnesium Sulphate Injection

Class

Answer 1

Hypomagnesaemia: Electrolyte and Tocolytic agent

Question 2

Magnesium Sulphate Injection

Presentation

Answer 2

1g in 2ml, 5g in 10mL ampoule

Question 3

Magnesium Sulphate Injection

Administration

Answer 3

Intravenous (IV)
Intraosseous (IO)

Question 4

Magnesium Sulphate Injection

Indications

Answer 4

Life Threatening Asthma
Torsades de pointes
Persistent Bronchospasm
Seizure associated with eclampsia

Question 5

Magnesium Sulphate Injection

Contraindications

Answer 5

None in cardiac arrest

KSAR

Question 6

Magnesium Sulphate Injection

Dosage

Answer 6

Adult:
Life Threatening Asthma: 2g IV in 100ml NaCL Infusion over 20 mins
Torsades (with pulse): 2g IV in 100ml NaCl infusion over 15 minutes
Bronchospasm: 2g IV in 100ml NaCl infusion over 20 minutes
Seizure with Eclampsia: 4g IV in 100ml NaCl infusion over 15 mins

Paed: not indicated

Question 7

Magnesium Sulphate Injection

Side Effects

Answer 7

Side Effects are Rare

Bradycardia (during infusion, give slowly)

Signs of Overdose include: Arrhythmias, Coma, Confusion, Drowsiness, Flushing of skin, Hypotension, Decreased deep tendon reflexes, Muscle Weakness, Nausea and Vomiting, Respiratory depression, Thirst

Question 8

Magnesium Sulphate Injection

Additional Info

Answer 8

5g in 10ml is equivalent to 20mmol/mg
Compatible with Glucose 5% or NaCL 0.9%.
Must be diluted prior to IV administration. Max COncentration must not exceed 20% (200mg/ml).
Monitoring Requirements: BP, Respiratory Rate, Urinary output and signs of overdose