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Dental Pathology > Odontogenic Cysts and Tumors > Flashcards

Odontogenic Cysts and Tumors Flashcards

1
Q

the most common developmental odontogenic cyst; originates secondary to the separation of the follicle from the crown of an unerupted tooth; enlargement occurs secondary to increased osmotic pressure within the lumen of the cyst

A

dentigerous cyst

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2
Q

M>F; 2nd and 3rd decades; mandibular 3rd molars most common, followed by maxillary canines; typically asymptomatic or a painless expansion; unilocular radiolucency; affected tooth may by displaced; may see root resorption of adjacent teeth

A

dentigerous cyst

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3
Q

soft tissue counterpart to the dentigerous cyst; occurs within the soft tissue overlying the alveolar bone

A

eruption cyst

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4
Q

under 10 years; typically involves mandibular molars; soft, translucent swelling of the gingival mucosa overlying an unerupted tooth

A

eruption cyst

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5
Q

traditionally, defined as a cyst that develops in place of a missing tooth; most are histologically diagnosed as odontogenic keratocyst

A

primordial cyst

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6
Q

distinct odontogenic cyst with specific histologic features and clinical behavior; arises from cell rests of the dental lamina; also associated with nevoid basal cell carcinoma syndrome

A

odontogenic keratocyst

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7
Q

M>F; 10-40 years; mandible>Maxilla; rarely cause expansion; unilocular to multilocular radiolucency

A

odontogenic keratocyst

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8
Q

not necessarily a clinical type of cyst, but an odontogenic cyst that microscopically has an orthokeratinized lining; markedly different clinical behavior from the odontogenic keratocyst

A

orthokeratinized odontogenic cyst

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9
Q

nonspecific; M>F; young adults; most involve the mandibular third molars; stratified squamous epithelium that exhibits a prominent layer of orthokeratin

A

orthokeratinized odontogenic cyst

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10
Q

autosomal dominant syndrome secondary to mutations in the patched (PTCH) tumor suppressor gene; high penetrance and variable expressivity; features multiple basal cell carcinomas of skin, odontogenic keratocysts, rib and vertebral anomalies, and intracranial calcifications

A

nevoid basal cell carcinoma syndrome (gorlin syndrome)

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11
Q

frontal and temporoparietal bossing; ocular hypertelorism; multiple and early basal cell carcinomas; palmar/plantar pitting; bifid ribs and other skeletal anomalies; calcified falx cerebri; multiple odontogenic keratocysts

A

nevoid basal cell carcinoma syndrome

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12
Q

superficial, keratin-filled cysts on the alveolar mucosa; arise from remnants of the dental lamina; similar in appearance (although not location) to Epstein’s pearls and Bohn’s nodules

A

gingival cyst of the newborn

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13
Q

maxilla>mandible; multiple small papules on the alveolar processes of neonates

A

gingival cyst of the newborn

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14
Q

soft tissue counterpart of the lateral periodontal cyst; derived from rests of the dental lamina; 5th-6th decade; mandibular canine-premolar area; blue to blue-gray dome-shaped swelling

A

gingival cyst of the adult

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15
Q

Developmental (not inflammtory) cysts that typically occurs along the lateral root surface; probably arises from rests of the dental lamina

A

lateral periodontal cyst

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16
Q

M>F; over age 30; mandibular canine-premolar area; well circumscribed radiolucency lateral to the root of a vital tooth (multilocular=botyroid)

A

lateral periodontal cyst

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17
Q

uncommon cyst, sometimes associated with other odontogenic tumors; if no cystic component is present, epithelial odontogenic ghost cell tumor or deninogenic ghost cell tumor is more appropriate

A

calcifying odontogenic cyst

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18
Q

avg. age 33; maxilla=mandible, often involving the maxillary incisor-canine region; may be peripheral; unilocular radiolucency, often with radiopaque structures within the lesion; most lesions are 2-4 cm; may see root resorption or divergence

A

calcifying odontogenic cyst

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19
Q

rare odontogenic cyst that shows features of glandular differentiation; also referred to as sialo-odontogenic cyst; the pathogenesis of this lesion is unknown; adults, mandible; strong predilection for the anterior portions of the jaws; may cross the midline

A

glandular odontogenic cyst

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20
Q

larger lesions capable of bony expansion; well-defined unilocular or multilocular radiolucency with a sclerotic rim; “hobnail” appearance to the luminal epithelial cells

A

glandular odontogenic cyst

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21
Q

may arise de novo or from malignant transformation of a pre-existing cyst or neoplasm; must rule out the possibility of metastatic carcinoma

A

carcinoma arising in odontogenic cysts

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22
Q

M>F, older patients; pain, swelling, parasthesia; irregular, ragged radiolucency

A

carcinoma arising in odontogenic cysts

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23
Q

the most common of the odontogenic epithelial neoplasms; arises from odontogenic epithelium

A

ameloblastoma

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24
Q

M=F, avg, age 34; asymptomatic swelling and expansion; posterior mandible; multilocular radiolucency, often associated with an unerupted tooth; resorption of roots is common

A

conventional ameloblastoma

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25
Q

ameloblastoma _ variant: predilection for anterior regions of jaws; radiographic resemblance to fribro-osseous lesions

A

desmoplastic

26
Q

_ pattern of ameloblastoma: islands of epithelium resembling the enamel organ with peripheral palisading and reverse polarity; central area resembling stellate reticulum

A

follicular

27
Q

_ pattern of ameloblastoma: anastomosing cords or sheets of cells; peripheral palisading and reverse polarity

A

plexiform

28
Q

_ pattern of ameloblastoma: squamous metaplasia within the tumor islands; keratin formation with occasional keratin pearls

A

acanthomatous

29
Q

_ pattern of ameloblastoma: cells within the islands are characterized by a granular cytoplasm

A

granular cell

30
Q

_ pattern of ameloblastoma: small islands and cords of odontogenic epithelium; dense fibrous stroma

A

desmoplastic

31
Q

_ pattern of ameloblastoma: nests of basaloid cells; peripheral islands more cuboidal than columnar

A

basal cell

32
Q

controversy regarding its definition; some feel that the lesion must be unilocular; others believe that multilocular is acceptable if the internal aspect is cystic; 10-15% of intraosseous ameloblastomas; previously thought less aggressive lesion with significantly lower recurrence rate, but this has recently been disputed

A

unicystic ameloblastoma

33
Q

younger patients; mandible, usually posterior; asymptomatic or painless swelling; circumscribed radiolucency

A

unicystic ameloblastoma

34
Q

uncommon variant; probably arises from submucosal rests of odontogenic epithelium or from the basal layer of the surface epithelium

A

peripheral ameloblastoma

35
Q

middle aged patients; painless gingival swelling; posterior mandible; may superficially erode bone, but overall no radiographic evidence of intraosseous lesion

A

peripheral ameloblastoma

36
Q

cytologically malignant ameloblastoma

A

ameloblastic carcinoma

37
Q

cytologically benign lesion showing metastasis

A

malignant ameloblastoma

38
Q

avg. age 30; metastatic site primarily the lungs, often after 10 years

A

malignant ameloblastoma

39
Q

sixth decade; ill-defined, destructive lucency

A

ameloblastic carcinoma

40
Q

uncommon tumor of uncertain histogenesis; thought to arise from stratum intermedium of enamel organ; other theories of histogenesis include rests of the dental lamina; posterior mandible; adults; painless, slow-growing swelling

A

calcifying epithelial odontogenic tumor

41
Q

often associated with impacted tooth; unilocular to multilocular; radiolucent, with or without “driven-snow” radiopacities; amyloid (congo red positive); Liesegang rings

A

calcifying epithelial odontogenic tumor

42
Q

benign odontogenic tumor that arises either from rests of the dental lamina of the rests of Malassez; the tumor tends to originate from within the periodontal ligament; probably diagnosed previously as a variant of ameloblastoma or even squamous cell carcinoma

A

squamous odontogenic tumor

43
Q

M=F, avg, age 38; painless or slightly painful swelling; mobility of associated teeth; triangular radiolucency; SOT-like proliferations

A

squamous odontogenic tumor

44
Q

originally included in the variants of ameloblastoma; thought derived from the enamel organ epithelium or possible remnants of the dental lamina; may produce dentinoid material, rarely enamel matrix

A

adenomatoid odontogenic tumor

45
Q

F>M; Most occur during the second decade; anterior maxilla; large lesions cause a painless expansion; circumscribed radiolucency involving the crown of an unerupted tooth; extends beyond the CEJ; may contain “snowflake” calcifications

A

adenomatoid odontogenic tumor

46
Q

thick fibrous capsule; aggregates of spindle shaped cells frequently in a whorled arrangement; variable numbers of duct-like structures; may contain small foci of calcification

A

adenomatoid odontogenic tumor

47
Q

mixed odontogenic tumor with both neoplastic epithelial and mesenchymal tissues; many of these may actually represent early developing odontomas

A

ameloblastic fibroma

48
Q

M>F, first 2 decades; posterior mandible; many associated with an unerupted tooth; unilocular or multilocular radiolucency

A

ameloblastic fibroma

49
Q

mesenchymal tissue resembling the dental papilla (pulp); odontogenic epithelium in islands or cords; epithelial portion resembles developing enamel organ

A

ameloblastic fibroma

50
Q

most common odontogenic tumor; two types: compound and complex

A

odontoma

51
Q

first 2 decades; large painless expansion; may see ghost cells

A

odontoma

52
Q

_ odontoma: posterior maxilla or mandible; calcified mass with the density of tooth structure

A

complex

53
Q

_ odontoma: anterior maxilla; multiple tooth-like structures with radiolucent rim

A

compound

54
Q

uncommon lesion with two described histologic subytpes, although this has recently been questioned; simple type and WHO type

A

odontogenic fibroma

55
Q

F>M, avg. age 40; maxilla, anterior to the first molar; expansion, loosening of teeth; unilocular to multilocular radiolucency; root resorption or divergence

A

odontogenic fibroma

56
Q

_ type of odontogenic fibroma: background of fine collagen fibrils with stellate fibroblasts; may see small foci of odontogenic epithelium

A

simple

57
Q

_ type of odontogenic fibroma: more cellular fibrous connective tissue; strands and nests of odontogenic epithelium

A

WHO

58
Q

soft tissue counterpart to the odontogenic fibroma; most similar to the WHO type

A

peripheral odontogenic fibroma

59
Q

slow growing gingival mass; may cause tooth displacement; radiograph may show areas of calcification within the soft tissue mass

A

peripheral odontogenic fibroma

60
Q

considered to be of odontogenic origin, resembling the odontogenic ectomesenchyme; histologically resembles the mesenchymal portion of a developing tooth

A

myxoma

61
Q

M=F, age 25-30; mandible>maxilla; asymptomatic expansion; “soap bubble” radiolucency

A

myxoma

Dental Pathology (22 decks)

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